(1E)-1-(1-benzofuran-2-yl)-N-(4-methoxyphenyl)ethan-1-imine

Base Information

• Chemical Name: (1E)-1-(1-benzofuran-2-yl)-N-(4-methoxyphenyl)ethan-1-imine
• CAS No.: 1170699-79-2
• Molecular Formula: C₁₇H₁₅NO₂
• Molecular Weight: 265.312
• Mol file: 1170699-79-2.mol

Synonyms:(1E)-1-(1-benzofuran-2-yl)-N-(4-methoxyphenyl)ethan-1-imine

Chemical Property of (1E)-1-(1-benzofuran-2-yl)-N-(4-methoxyphenyl)ethan-1-imine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

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Technology Process of (1E)-1-(1-benzofuran-2-yl)-N-(4-methoxyphenyl)ethan-1-imine

There total 1 articles about (1E)-1-(1-benzofuran-2-yl)-N-(4-methoxyphenyl)ethan-1-imine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

1-(benzo[b]furan-2-yl)ethanone (1646-26-0) + 4-methoxy-aniline (104-94-9) → (1E)-1-(1-benzofuran-2-yl)-N-(4-methoxyphenyl)ethan-1-imine (1170699-79-2)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 5h; Reflux; Molecular sieve;

DOI:10.1021/jo900561h

Reference yield: 56.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + (1E)-1-(1-benzofuran-2-yl)-N-(4-methoxyphenyl)ethan-1-imine (1170699-79-2) → 1-(3-(1-phenylethyl)benzofuran-2-yl)ethan-1-one

Guidance literature:

(1E)-1-(1-benzofuran-2-yl)-N-(4-methoxyphenyl)ethan-1-imine; With cobalt(II) bromide; cyclohexylmagnesium bromide; P(p-C₆H₄F)3; In tetrahydrofuran; for 0.5h; Schlenk technique; Inert atmosphere; Cooling with ice;

styrene; In tetrahydrofuran; at 20 ℃; for 28h; regioselective reaction; Schlenk technique; Inert atmosphere; Cooling with ice;

DOI:10.1246/cl.130508

Reference yield: 32.0%

(1E)-1-(1-benzofuran-2-yl)-N-(4-methoxyphenyl)ethan-1-imine (1170699-79-2) → (E)-N-(4-methoxyphenyl)benzofuran-2-carbimidoyl cyanide

Guidance literature:

With [bis(acetoxy)iodo]benzene; trimethylsilylazide; sodium bromide; In dimethyl sulfoxide; at 20 ℃; for 12h;

DOI:10.1002/chem.201301933

upstream raw materials:

1-(benzo[b]furan-2-yl)ethanone

4-methoxy-aniline

Downstream raw materials:

(-)-N-[1-(benzofuran-2-yl)ethyl]-N-(4-methoxyphenyl)amine

N-[1-(benzofuran-2-yl)ethyl]-N-(4-methoxyphenyl)amine

1-(3-phenylethylbenzofuran-2-yl)ethan-1-one