2,3'-ANHYDRO-1-(2'-DEOXY-5'-O-METHYLSULFONYL-BETA-D-THREO-PENTOFURANOSYL)-THYMINE

Base Information

Chemical Name:2,3'-ANHYDRO-1-(2'-DEOXY-5'-O-METHYLSULFONYL-BETA-D-THREO-PENTOFURANOSYL)-THYMINE
CAS No.:15981-86-9
Molecular Formula:C11H14 N2 O6 S
Molecular Weight:302.308
Hs Code.:
Mol file:15981-86-9.mol

Synonyms:2,5-Methano-5H,9H-pyrimido[2,1-b][1,5,3]dioxazepin-9-one,2,3-dihydro-3-(hydroxymethyl)-8-methyl-, methanesulfonate (7CI);2,5-Methano-5H,9H-pyrimido[2,1-b][1,5,3]dioxazepin-9-one,2,3-dihydro-3-(hydroxymethyl)-8-methyl-, methanesulfonate (ester) (8CI);2,5-Methano-5H,9H-pyrimido[2,1-b][1,5,3]dioxazepin-9-one,2,3-dihydro-8-methyl-3-[[(methylsulfonyl)oxy]methyl]-, [2R-(2a,3b,5a)]-; Thymine, 2,3'-anhydro-1-(2-deoxy-b-D-threo-pentofuranosyl)-, 5'-methanesulfonate;5'-O-Methanesulfonyl-2'-deoxy-2,3'-anhydrothymidine

Suppliers and Price of 2,3'-ANHYDRO-1-(2'-DEOXY-5'-O-METHYLSULFONYL-BETA-D-THREO-PENTOFURANOSYL)-THYMINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2,3'-ANHYDRO-1-(2'-DEOXY-5'-O-METHYLSULFONYL-BETA-D-THREO-PENTOFURANOSYL)-THYMINE 95.00%
5MG
$ 495.84

Total 7 raw suppliers

Chemical Property of 2,3'-ANHYDRO-1-(2'-DEOXY-5'-O-METHYLSULFONYL-BETA-D-THREO-PENTOFURANOSYL)-THYMINE

Chemical Property:

PSA：105.10000
LogP:0.65720

Purity/Quality:

97% ^*data from raw suppliers

2,3'-ANHYDRO-1-(2'-DEOXY-5'-O-METHYLSULFONYL-BETA-D-THREO-PENTOFURANOSYL)-THYMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,3'-ANHYDRO-1-(2'-DEOXY-5'-O-METHYLSULFONYL-BETA-D-THREO-PENTOFURANOSYL)-THYMINE

There total 6 articles about 2,3'-ANHYDRO-1-(2'-DEOXY-5'-O-METHYLSULFONYL-BETA-D-THREO-PENTOFURANOSYL)-THYMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 56822-33-4
3',5'-di-O-mesylthymidine

: 15981-86-9
1-(2,3'-Anhydro-5'-O-methylsulfonyl-2-deoxy-β-D-threo-pentofuranosyl)thymine

Guidance literature:: With triethylamine; In ethanol; for 30h; Reflux;
DOI:10.1002/chem.201000785

Reference yield: 85.0%

: 56822-33-4
1-(2-Desoxy-3,5-di-O-mesyl-β-D-ribofuranosyl)-thymin

: 15981-86-9
1-(2,3'-Anhydro-5'-O-methylsulfonyl-2-deoxy-β-D-threo-pentofuranosyl)thymine

Guidance literature:: With potassium hydroxide; In ethanol; for 1h; Heating;

Reference yield: 35.0%

: 56822-33-4
3',5'-di-O-mesylthymidine

: 15981-86-9
5'-O-mesyl-2,3'-anhydro-thymidine

: 140175-70-8
1,2,5,6-tetradeoxy-1-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)-β-D-erythro-hexofuranurono-6,3-sultone

: 5983-11-9
2-methyl-5-(thymin-1-yl)furan

: 52523-38-3
(R)-1-(2,5-dihydro-5-methylene-2-furanyl)-5-methyl-2,4(1H,3H)-pyrimidinedione

Guidance literature:: With lithium acetylide-ethylenediamine complex; In dimethyl sulfoxide; for 16h; Further byproducts given; Ambient temperature;
DOI:10.1021/jo00036a014