5-Methyl-1-[(2R)-5-methylidene-2,5-dihydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione

Base Information

Chemical Name:5-Methyl-1-[(2R)-5-methylidene-2,5-dihydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione
CAS No.:52523-38-3
Molecular Formula:C10H10N2O3
Molecular Weight:206.201
Hs Code.:
DSSTox Substance ID:DTXSID20562110
Nikkaji Number:J452.624D
Wikidata:Q82446115

Synonyms:52523-38-3;SCHEMBL19871062;DTXSID20562110;5-Methyl-1-[(2R)-5-methylidene-2,5-dihydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione

Suppliers and Price of 5-Methyl-1-[(2R)-5-methylidene-2,5-dihydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-Methyl-1-[(2R)-5-methylidene-2,5-dihydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:206.06914219
Heavy Atom Count:15
Complexity:409

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CN(C(=O)NC1=O)C2C=CC(=C)O2
Isomeric SMILES:CC1=CN(C(=O)NC1=O)[C@H]2C=CC(=C)O2

Technology Process of 5-Methyl-1-[(2R)-5-methylidene-2,5-dihydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione

There total 1 articles about 5-Methyl-1-[(2R)-5-methylidene-2,5-dihydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 56822-33-4
3',5'-di-O-mesylthymidine

: 15981-86-9
5'-O-mesyl-2,3'-anhydro-thymidine

: 140175-70-8
1,2,5,6-tetradeoxy-1-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)-β-D-erythro-hexofuranurono-6,3-sultone

: 5983-11-9
2-methyl-5-(thymin-1-yl)furan

: 52523-38-3
(R)-1-(2,5-dihydro-5-methylene-2-furanyl)-5-methyl-2,4(1H,3H)-pyrimidinedione

Guidance literature:: With lithium acetylide-ethylenediamine complex; In dimethyl sulfoxide; for 16h; Further byproducts given; Ambient temperature;
DOI:10.1021/jo00036a014

Reference yield:

: 52523-38-3
(R)-1-(2,5-dihydro-5-methylene-2-furanyl)-5-methyl-2,4(1H,3H)-pyrimidinedione

: 65-71-4,28806-14-6,691841-57-3
thymin

: 5983-11-9
2-methyl-5-(thymin-1-yl)furan

Guidance literature:: With pyridinium p-toluenesulfonate;
DOI:10.1016/j.tet.2007.03.059

Reference yield:

: 93-97-0
benzoic acid anhydride

: 52523-38-3
(R)-1-(2,5-dihydro-5-methylene-2-furanyl)-5-methyl-2,4(1H,3H)-pyrimidinedione

: C₁₇H₁₄N₂O₅

Guidance literature:: (R)-1-(2,5-dihydro-5-methylene-2-furanyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at -78 - 20 ℃;

benzoic acid anhydride; With triethylamine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1021/op970126p