3-HYDROXYQUINOLINE-2-CARBOXYLIC ACID

Base Information

Chemical Name:3-HYDROXYQUINOLINE-2-CARBOXYLIC ACID
CAS No.:15462-45-0
Molecular Formula:C10H7NO3
Molecular Weight:189.17
Hs Code.:2933499090
Mol file:15462-45-0.mol

Synonyms:3-Hydroxy-2-quinolinecarboxylic acid;Quinaldicacid, 3-hydroxy- (8CI);3-Hydroxyquinaldic acid;

Suppliers and Price of 3-HYDROXYQUINOLINE-2-CARBOXYLIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Hydroxyquinoline-2-carboxylicacid
10mg
$ 75.00

TRC
3-Hydroxyquinoline-2-carboxylicacid
5mg
$ 50.00

Chemenu
3-Hydroxyquinoline-2-carboxylicacid 97%
1g
$ 860.00

Alichem
3-Hydroxyquinoline-2-carboxylicacid
1g
$ 1379.54

Alichem
3-Hydroxyquinoline-2-carboxylicacid
250mg
$ 531.19

Total 19 raw suppliers

Chemical Property of 3-HYDROXYQUINOLINE-2-CARBOXYLIC ACID

Chemical Property:

Vapor Pressure:1.32E-06mmHg at 25°C
Melting Point:187-190 °C (decomp)
Refractive Index:1.73
Boiling Point:384.7 °C at 760 mmHg
PKA:0.02±0.30(Predicted)
Flash Point:186.5 °C
PSA：70.42000
Density:1.48 g/cm³
LogP:1.63860
Storage Temp.:2-8°C
Solubility.:DMSO (Slightly, Heated), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

3-Hydroxyquinoline-2-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 3-Hydroxyquinoline-2-carboxylic Acid is a useful intermediate in the chromophore biosynthesis of quinomycin family antibiotics and in the total synthesis of Echinomycin and its analogs

Technology Process of 3-HYDROXYQUINOLINE-2-CARBOXYLIC ACID

There total 13 articles about 3-HYDROXYQUINOLINE-2-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 171917-54-7
Methyl 3-(benzyloxy)quinoline-2-carboxylate

: 15462-45-0
Methyl 3-hydroxyquinoline-2-carboxylate

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 25 ℃; for 5h; under 760 Torr;
DOI:10.1021/jo00127a055

Reference yield: 92.0%

: 14370-68-4
ethyl 3-hydroxyquinoline-2-carboxylate

: 15462-45-0
Methyl 3-hydroxyquinoline-2-carboxylate

Guidance literature:: With potassium hydroxide; In tetrahydrofuran; methanol; water; at 20 ℃; for 4h;
DOI:10.1021/acs.jnatprod.5b00428

Reference yield: 70.0%

: 847547-93-7
3-(methoxymethoxy)-2-methylquinoline

: 15462-45-0
Methyl 3-hydroxyquinoline-2-carboxylate

Guidance literature:: 3-(methoxymethoxy)-2-methylquinoline; With selenium(IV) oxide; In 1,4-dioxane; for 1h; Heating;

With formic acid; dihydrogen peroxide; In water; at 0 - 10 ℃;
DOI:10.1016/j.tet.2004.12.011