ethyl 3,4-bis{4-[4-(5-octylpyrimidin-2-yl)phenyloxy]butyloxy}benzoate

Base Information

• Chemical Name: ethyl 3,4-bis{4-[4-(5-octylpyrimidin-2-yl)phenyloxy]butyloxy}benzoate
• CAS No.: 872002-32-9
• Molecular Formula: C₅₃H₇₀N₄O₆
• Molecular Weight: 859.162
• Mol file: 872002-32-9.mol

Synonyms:ethyl 3,4-bis{4-[4-(5-octylpyrimidin-2-yl)phenyloxy]butyloxy}benzoate

Chemical Property of ethyl 3,4-bis{4-[4-(5-octylpyrimidin-2-yl)phenyloxy]butyloxy}benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 3,4-bis{4-[4-(5-octylpyrimidin-2-yl)phenyloxy]butyloxy}benzoate

There total 2 articles about ethyl 3,4-bis{4-[4-(5-octylpyrimidin-2-yl)phenyloxy]butyloxy}benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2-[4-(4-bromobutyloxy)phenyl]-5-octylpyrimidine (872002-31-8) + Ethyl protocatechuate (3943-89-3) → ethyl 3,4-bis{4-[4-(5-octylpyrimidin-2-yl)phenyloxy]butyloxy}benzoate (872002-32-9)

Guidance literature:

With potassium carbonate; potassium iodide; In cyclohexanone; at 145 ℃; for 12h;

DOI:10.1080/15421400590956225

Reference yield:

4-(5-octylpyrimidin-2-yl)phenol (58415-63-7) → ethyl 3,4-bis{4-[4-(5-octylpyrimidin-2-yl)phenyloxy]butyloxy}benzoate (872002-32-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / potassium carbonate / cyclohexanone / 6 h / 80 °C

2: 72 percent / K₂CO₃; KI / cyclohexanone / 12 h / 145 °C

With potassium carbonate; potassium iodide; In cyclohexanone;

DOI:10.1080/15421400590956225

Reference yield: 92.0%

ethyl 3,4-bis{4-[4-(5-octylpyrimidin-2-yl)phenyloxy]butyloxy}benzoate (872002-32-9) → 3,4-bis{4-[4-(5-octylpyrimidin-2-yl)phenyloxy]butyloxy}benzoic acid (872002-33-0)

Guidance literature:

With potassium hydroxide; In ethanol; for 2h; Heating;

DOI:10.1080/15421400590956225

upstream raw materials:

2-[4-(4-bromobutyloxy)phenyl]-5-octylpyrimidine

Ethyl protocatechuate

4-(5-octylpyrimidin-2-yl)phenol

Downstream raw materials:

3,4-bis{4-[4-(5-octylpyrimidin-2-yl)phenyloxy]butyloxy}benzoic acid