5beta-Androstan-3beta-ol

Base Information

• Chemical Name: 5beta-Androstan-3beta-ol
• CAS No.: 15360-52-8
• Molecular Formula: C₁₉H₃₂O
• Molecular Weight: 276.462
• DSSTox Substance ID: DTXSID80508135
• Nikkaji Number: J146.341A
• Wikidata: Q82364848
• Mol file: 15360-52-8.mol

Synonyms:5beta-Androstan-3beta-ol;15360-52-8;5-Beta-androstan-3-beta-ol;(3S,5R,8S,9S,10S,13S,14S)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol;(3beta,5beta)-Androstan-3-ol;5.beta.-Androstan-3.beta.-ol;Androstan-3-ol, (3.beta.,5.beta.)-;SCHEMBL6941369;DTXSID80508135;DJTOLSNIKJIDFF-KYQPOWKGSA-N;3.beta.-Hydroxy-5.beta.-androstane;AKOS015910530

Chemical Property of 5beta-Androstan-3beta-ol

Chemical Property:

• PSA: 20.23000
• LogP: 4.78010
• XLogP3: 5.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 276.245315640
• Heavy Atom Count: 20
• Complexity: 391

Purity/Quality:

97% ^*data from raw suppliers

5-BETA-ANDROSTAN-3BETA-OL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC12CCCC1C3CCC4CC(CCC4(C3CC2)C)O
• Isomeric SMILES: C[C@@]12CCC[C@H]1[C@@H]3CC[C@@H]4C[C@H](CC[C@@]4([C@H]3CC2)C)O

Technology Process of 5beta-Androstan-3beta-ol

There total 46 articles about 5beta-Androstan-3beta-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

androst-5-en-3β-ol (1476-64-8,25706-90-5) → 5α-androstan-3β-ol (1224-93-7,7657-50-3,7753-89-1,10085-14-0,15360-52-8,15360-53-9,36216-01-0,36216-02-1,1224-92-6)

Guidance literature:

With platinum(IV) oxide; hydrogen; acetic acid; In dichloromethane; for 16h; under 3102.97 Torr;

DOI:10.1016/j.bmcl.2010.10.044

Reference yield: 94.0%

Epiandrosterone (481-29-8) → 5α-androstan-3β-ol (1224-93-7,7657-50-3,7753-89-1,10085-14-0,15360-52-8,15360-53-9,36216-01-0,36216-02-1,1224-92-6)

Guidance literature:

With potassium hydroxide; hydrazine hydrate; In diethylene glycol;

DOI:10.1021/ja00310a046

Reference yield: 82.0%

(3β,5α,13β)-3-hydroxy-18-norandrostan-17-one (4732-78-9) → 5α-androstan-3β-ol (1224-93-7,7657-50-3,7753-89-1,10085-14-0,15360-52-8,15360-53-9,36216-01-0,36216-02-1,1224-92-6)

Guidance literature:

With hydrazine hydrate; potassium hydroxide; In diethylene glycol; at 200 - 220 ℃; for 16h;

DOI:10.1002/ejoc.201100390

upstream raw materials:

Epiandrosterone

3β-hydroxy-5α-androstan-16-one

5α-androst-16-en-3β-ol

androst-5-en-3β-ol

Downstream raw materials:

androstan-3-one

2.3-seco-5α-androstanedioic acid-(2.3)

5α-Androstan-3β-ol-tosylat

dibenzyl 5α-androstan-3β-yl phosphate