4-methyl-2-(2-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-ylthio)acetamido)pentanehydrazide

Base Information

Chemical Name:4-methyl-2-(2-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-ylthio)acetamido)pentanehydrazide
CAS No.:1638842-89-3
Molecular Formula:C₂₂H₂₅N₅O₃S
Molecular Weight:439.538
Hs Code.:

Synonyms:4-methyl-2-(2-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-ylthio)acetamido)pentanehydrazide

Suppliers and Price of 4-methyl-2-(2-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-ylthio)acetamido)pentanehydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-methyl-2-(2-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-ylthio)acetamido)pentanehydrazide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-methyl-2-(2-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-ylthio)acetamido)pentanehydrazide

There total 5 articles about 4-methyl-2-(2-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-ylthio)acetamido)pentanehydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1638842-71-3
methyl 4-methyl-2-(2-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-ylthio)acetamido)pentanoate

: 1638842-89-3
4-methyl-2-(2-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-ylthio)acetamido)pentanehydrazide

Guidance literature:: With hydrazine hydrate; In methanol; at 78 ℃; for 4h;
DOI:10.1248/cpb.c14-00158

Reference yield:

: 18741-24-7
3-phenyl-2-thioxo-2,3-dihydro-1H-quinazolin-4-one

: 1638842-89-3
4-methyl-2-(2-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-ylthio)acetamido)pentanehydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / ethanol / 2 h / 25 °C

2: dicyclohexyl-carbodiimide; benzotriazol-1-ol / acetonitrile / 10 h / -5 - 20 °C

3: hydrazine hydrate / methanol / 4 h / 78 °C

With benzotriazol-1-ol; hydrazine hydrate; dicyclohexyl-carbodiimide; sodium hydroxide; In methanol; ethanol; acetonitrile;
DOI:10.1248/cpb.c14-00158

Reference yield:

: (4-Oxo-3-phenyl-3,4-dihydro-quinazolin-2-ylsulfanyl)-acetic acid methyl ester

: 1638842-89-3
4-methyl-2-(2-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-ylthio)acetamido)pentanehydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / water; methanol / 3 h / 25 °C

2: dicyclohexyl-carbodiimide; benzotriazol-1-ol / acetonitrile / 10 h / -5 - 20 °C

3: hydrazine hydrate / methanol / 4 h / 78 °C

With benzotriazol-1-ol; hydrazine hydrate; dicyclohexyl-carbodiimide; sodium hydroxide; In methanol; water; acetonitrile;
DOI:10.1248/cpb.c14-00158