4-Azoniaspiro[3.5]nonan-2-ol chloride

Base Information

Chemical Name:4-Azoniaspiro[3.5]nonan-2-ol chloride
CAS No.:15285-58-2
Molecular Formula:C₈H₁₆NO*Cl
Molecular Weight:177.674
Hs Code.:
European Community (EC) Number:855-076-5
ChEMBL ID:CHEMBL1353051
Mol file:15285-58-2.mol

Synonyms:15285-58-2;4-azoniaspiro[3.5]nonan-2-ol;chloride;2-Hydroxy-4-azoniaspiro[3.5]nonane Chloride;4-AZONIASPIRO[3.5]NONANE, 2-HYDROXY-,CHLORIDE;4-Azoniaspiro[3.5]nonane, 2-hydroxy-, chloride (1:1);4-azoniaspiro[3.5]nonan-2-ol chloride;MLS000037900;SCHEMBL5699235;CHEMBL1353051;HMS2480G21;AKOS030508386;SB18281;SMR000057745;CS-0447036;2-Hydroxy-4-azaspiro[3.5]Nonan-4-ium chloride;EN300-6491294;2-hydroxy-4|E?-azaspiro[3.5]nonan-4-ylium chloride;2-hydroxy-4lambda-azaspiro[3.5]nonan-4-ylium chloride;2-hydroxy-4lambda5-azaspiro[3.5]nonan-4-ylium chloride;Z1504674728

Suppliers and Price of 4-Azoniaspiro[3.5]nonan-2-ol chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Hydroxy-4-azoniaspiro[3.5]nonaneChloride
100mg
$ 1260.00

Total 7 raw suppliers

Chemical Property of 4-Azoniaspiro[3.5]nonan-2-ol chloride

Chemical Property:

PSA：20.23000
LogP:-2.67560
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:177.0920418
Heavy Atom Count:11
Complexity:121

Purity/Quality:

99.9% ^*data from raw suppliers

2-Hydroxy-4-azoniaspiro[3.5]nonaneChloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC[N+]2(CC1)CC(C2)O.[Cl-]
Uses 2-Hydroxy-4-azoniaspiro[3.5]nonane Chloride is used as a reagent in the synthesis of polyfunctional phosphorodithioates and its derivatives via nucleophilic ring opening of azetidinium ions. 2-Hydroxy-4-azoniaspiro[3.5]nonane Chloride is also a reagent in the synthesis of Arimoclomol Maleic Acid (A771270); an orally administered drug used to treat amyotrophic lateral sclerosis.

Technology Process of 4-Azoniaspiro[3.5]nonan-2-ol chloride

There total 2 articles about 4-Azoniaspiro[3.5]nonan-2-ol chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 110-89-4
piperidine

: 106-89-8,24969-06-0,13403-37-7
epichlorohydrin

: 15285-58-2
2-Hydroxy-4-azoniaspiro<3.5>nonane

Guidance literature:: In methanol; at 65 ℃;
DOI:10.1039/c7ob02578e

Reference yield:

: 15285-58-2
2-Hydroxy-4-azoniaspiro<3.5>nonane

Guidance literature:: 1-Chlor-3-piperidyl-2-propanol, in Acetonitril;
DOI:10.1021/jo01266a010

Reference yield:

: 100-39-0
benzyl bromide

: 15285-58-2
2-Hydroxy-4-azoniaspiro<3.5>nonane

: 2-benzyloxy-4-azonia-spiro[3.5]nonane; bromide

Guidance literature:: benzyl bromide; 2-Hydroxy-4-azoniaspiro<3.5>nonane; With potassium hydroxide; In dimethyl sulfoxide; at 20 ℃; for 12h;

With calcium hydride; In dimethyl sulfoxide; at 60 ℃; for 2h;
DOI:10.1016/S0040-4020(99)00698-5