CYCLO(-GLY-HIS)

Base Information

Chemical Name:CYCLO(-GLY-HIS)
CAS No.:15266-88-3
Molecular Formula:C₈H₁₀N₄O₂
Molecular Weight:194.193
Hs Code.:2933990090
Mol file:15266-88-3.mol

Synonyms:2,5-Piperazinedione,3-(1H-imidazol-4-ylmethyl)-, (3S)- (9CI); 2,5-Piperazinedione,3-(1H-imidazol-4-ylmethyl)-, (S)-; 2,5-Piperazinedione,3-(imidazol-4-ylmethyl)-, L- (8CI); Cyclo(glycyl-L-histidyl) (7CI);Cyclo(glycylhistidine)

Suppliers and Price of CYCLO(-GLY-HIS)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Cyclo(-Gly-L-His)
100mg
$ 150.00

Crysdot
(S)-3-((1H-Imidazol-5-yl)methyl)piperazine-2,5-dione 95+%
1g
$ 508.00

Chemenu
(S)-3-((1H-imidazol-5-yl)methyl)piperazine-2,5-dione 95%
1g
$ 480.00

Biosynth Carbosynth
Cyclo(-Gly-L-His)
1 g
$ 488.30

Biosynth Carbosynth
Cyclo(-Gly-L-His)
500 mg
$ 225.00

Biosynth Carbosynth
Cyclo(-Gly-L-His)
250 mg
$ 140.00

Biosynth Carbosynth
Cyclo(-Gly-L-His)
100 mg
$ 101.00

Biosynth Carbosynth
Cyclo(-Gly-L-His)
50 mg
$ 63.00

Total 14 raw suppliers

Chemical Property of CYCLO(-GLY-HIS)

Chemical Property:

Boiling Point:758.7±50.0 °C(Predicted)
PKA:12.71±0.40(Predicted)
PSA：86.88000
Density:1.373±0.06 g/cm3(Predicted)
LogP:-0.77560
Storage Temp.:-15°C

Purity/Quality:

99% ^*data from raw suppliers

Cyclo(-Gly-L-His) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Cyclo(-Gly-L-His) is a cytotoxic agents with antithrombotic effects.

Technology Process of CYCLO(-GLY-HIS)

There total 3 articles about CYCLO(-GLY-HIS) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 2578-58-7
N-(L-histidyl)glycine

: 15266-88-3
Cyclo(glycyl-L-histidyl)

Guidance literature:: With 14C₂H₇N*14H⁽¹⁺⁾*2H₂O*2O^(2-)*2Zr⁽⁴⁺⁾*O₁₂₂P₄W₃₄^(18-); In dimethyl sulfoxide; at 70 ℃; for 24h;
DOI:10.1021/acscatal.9b03415

Reference yield:

: 37941-52-9
Cbz-Gly-His-OMe

: 15266-88-3
Cyclo(glycyl-L-histidyl)

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 10percent Pd/C / ethanol

2: methanol / 18 h / Heating

With hydrogen; palladium on activated charcoal; In methanol; ethanol;