3-{3-[(4-methylcyclohex-3-enylcarbonyl)amino]-4-oxo-3,4-dihydroquinazolin-2-yl}propanoic acid

Base Information

Chemical Name:3-{3-[(4-methylcyclohex-3-enylcarbonyl)amino]-4-oxo-3,4-dihydroquinazolin-2-yl}propanoic acid
CAS No.:1385033-58-8
Molecular Formula:C₁₉H₂₁N₃O₄
Molecular Weight:355.393
Hs Code.:

Synonyms:3-{3-[(4-methylcyclohex-3-enylcarbonyl)amino]-4-oxo-3,4-dihydroquinazolin-2-yl}propanoic acid

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Chemical Property of 3-{3-[(4-methylcyclohex-3-enylcarbonyl)amino]-4-oxo-3,4-dihydroquinazolin-2-yl}propanoic acid

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Technology Process of 3-{3-[(4-methylcyclohex-3-enylcarbonyl)amino]-4-oxo-3,4-dihydroquinazolin-2-yl}propanoic acid

There total 2 articles about 3-{3-[(4-methylcyclohex-3-enylcarbonyl)amino]-4-oxo-3,4-dihydroquinazolin-2-yl}propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

: 108-30-5
succinic acid anhydride

: 1322137-97-2
C₁₆H₁₉N₃O₄

: 1385033-58-8
3-{3-[(4-methylcyclohex-3-enylcarbonyl)amino]-4-oxo-3,4-dihydroquinazolin-2-yl}propanoic acid

Guidance literature:: In acetic acid; for 10h; Reflux;
DOI:10.1007/s10593-012-0997-z

Reference yield:

: 108-30-5
succinic acid anhydride

: 1385033-59-9
C₁₅H₁₉N₃O₂

: 1385033-58-8
3-{3-[(4-methylcyclohex-3-enylcarbonyl)amino]-4-oxo-3,4-dihydroquinazolin-2-yl}propanoic acid

Guidance literature:: In acetic acid; for 6h; Reflux;
DOI:10.1007/s10593-012-0997-z

Reference yield: 82.0%

: 1385033-58-8
3-{3-[(4-methylcyclohex-3-enylcarbonyl)amino]-4-oxo-3,4-dihydroquinazolin-2-yl}propanoic acid

: 88-17-5
2-(trifluoromethyl)benzenamine

: 1385033-62-4
C₂₆H₂₅F₃N₄O₃

Guidance literature:: 3-{3-[(4-methylcyclohex-3-enylcarbonyl)amino]-4-oxo-3,4-dihydroquinazolin-2-yl}propanoic acid; With chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran; at -10 ℃; for 0.333333h;

2-(trifluoromethyl)benzenamine; In tetrahydrofuran; at -10 - 20 ℃; for 6h;
DOI:10.1007/s10593-012-0997-z