Technology Process of benzyl (+/-)-cis-2-acetoxycyclobutanecarboxylate
There total 3 articles about benzyl (+/-)-cis-2-acetoxycyclobutanecarboxylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
disodium hydrogenphosphate; dihydrogen peroxide; trifluoroacetic anhydride;
In
dichloromethane;
for 2h;
Heating;
DOI:10.1021/jm00351a016
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 56 percent / (COCl)2, pyridine / benzene / 24 h / 0 - 55 °C
2: 1.) CdCl2 / 1.) Et2O, dimethoxyethane, a.) 0 deg C, 1 h, b.) 25 deg C, 23 h, 2.) dimethoxyethane, Et2O, a.) 0 deg C, 1 h, b.) 72 deg C, 107 h
3: 81 percent / trifluoroacetic anhydride, 90percent H2O2, Na2HPO4 / CH2Cl2 / 2 h / Heating
With
pyridine; disodium hydrogenphosphate; oxalyl dichloride; dihydrogen peroxide; trifluoroacetic anhydride; cadmium(II) chloride;
In
dichloromethane; benzene;
DOI:10.1021/jm00351a016
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) CdCl2 / 1.) Et2O, dimethoxyethane, a.) 0 deg C, 1 h, b.) 25 deg C, 23 h, 2.) dimethoxyethane, Et2O, a.) 0 deg C, 1 h, b.) 72 deg C, 107 h
2: 81 percent / trifluoroacetic anhydride, 90percent H2O2, Na2HPO4 / CH2Cl2 / 2 h / Heating
With
disodium hydrogenphosphate; dihydrogen peroxide; trifluoroacetic anhydride; cadmium(II) chloride;
In
dichloromethane;
DOI:10.1021/jm00351a016
