2-Fluoro-2'-methoxybiphenyl

Base Information

Chemical Name:2-Fluoro-2'-methoxybiphenyl
CAS No.:80254-65-5
Molecular Formula:C₁₃H₁₁FO
Molecular Weight:202.228
Hs Code.:
DSSTox Substance ID:DTXSID801300291
Nikkaji Number:J2.866.586E

Synonyms:2-Fluoro-2'-methoxybiphenyl;SCHEMBL22285911;DTXSID801300291;2-Fluoro-2'-methoxy-1,1'-biphenyl;80254-65-5

Suppliers and Price of 2-Fluoro-2'-methoxybiphenyl

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-Fluoro-2'-methoxybiphenyl

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:202.079393132
Heavy Atom Count:15
Complexity:195

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC=C1C2=CC=CC=C2F

Technology Process of 2-Fluoro-2'-methoxybiphenyl

There total 1 articles about 2-Fluoro-2'-methoxybiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: 348-51-6
1-chloro-2-fluorobenzene

: 578-57-4
2-bromoanisole

: 388-82-9
2,2'-difluorobiphenyl

: 4877-93-4
2,2'-Dimethoxybiphenyl

: 80254-65-5
2-fluoro-2'-methoxy-1,1'-biphenyl

Guidance literature:: With NaH-t-AmONa-Ni(OAc)2-bpy-KI; In tetrahydrofuran; benzene; at 63 ℃; for 2.5h; Yields of byproduct given;
DOI:10.1021/jo00281a028

Reference yield:

: 80254-65-5
2-fluoro-2'-methoxy-1,1'-biphenyl

: 73183-34-3
bis(pinacol)diborane

: 2-(2-fluoro-2'-methoxy-biphenyl-4-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

: C₁₉H₂₂BFO₃

Guidance literature:: With trans-(^iPrPNP)Co(H)₂BPin; In tetrahydrofuran; at 50 ℃; for 24h; Overall yield = 70 %; Overall yield = 0.126 g; Inert atmosphere; Glovebox;
DOI:10.1021/jacs.6b13346