7,16-bis(2-hydroxy-5-nitrobenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane

Base Information

• Chemical Name: 7,16-bis(2-hydroxy-5-nitrobenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane
• CAS No.: 77857-33-1
• Molecular Formula: C₂₆H₃₆N₄O₁₀
• Molecular Weight: 564.593
• Mol file: 77857-33-1.mol

Synonyms:7,16-bis(2-hydroxy-5-nitrobenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane

Chemical Property of 7,16-bis(2-hydroxy-5-nitrobenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane

Chemical Property:

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Technology Process of 7,16-bis(2-hydroxy-5-nitrobenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane

There total 1 articles about 7,16-bis(2-hydroxy-5-nitrobenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

Koshlands reagent I (772-33-8) + 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane (23978-55-4) → 7,16-bis(2-hydroxy-5-nitrobenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane (77857-33-1)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In acetonitrile; for 12h; Heating;

DOI:10.1021/jo9816212

Reference yield: 98.0%

7,16-bis(2-hydroxy-5-nitrobenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane (77857-33-1) → 7,16-bis(5-amino-2-hydroxybenzyl)-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane

Guidance literature:

With hydrogen; platinum(IV) oxide; In methanol; for 5h; under 2585.74 - 3102.89 Torr;

DOI:10.1021/jo9816212

upstream raw materials:

Koshlands reagent I

1,4,10,13-tetraoxa-7,16-diazacyclooctadecane