(R)-(-)-3-(dimethylphenylsilyl)-3-phenyl-1-butene

Base Information

Chemical Name:(R)-(-)-3-(dimethylphenylsilyl)-3-phenyl-1-butene
CAS No.:945684-77-5
Molecular Formula:C₁₈H₂₂Si
Molecular Weight:266.458
Hs Code.:

Synonyms:(R)-(-)-3-(dimethylphenylsilyl)-3-phenyl-1-butene

Suppliers and Price of (R)-(-)-3-(dimethylphenylsilyl)-3-phenyl-1-butene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-(-)-3-(dimethylphenylsilyl)-3-phenyl-1-butene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-(-)-3-(dimethylphenylsilyl)-3-phenyl-1-butene

There total 3 articles about (R)-(-)-3-(dimethylphenylsilyl)-3-phenyl-1-butene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 945684-61-7
(E)-3-(dimethylphenylsilyl)-1-(diethoxyphosphoryloxy)-2-butene

: 1078-58-6
diphenylzinc

: 945684-77-5
(R)-(-)-3-(dimethylphenylsilyl)-3-phenyl-1-butene

: (S)-(+)-3-(dimethylphenylsilyl)-3-phenyl-1-butene

Guidance literature:: With copper(I) trifluoromethanesulfonate benzene; chiral N-heterocyclic carbene-based silver catalyst; In tetrahydrofuran; at -78 ℃; for 24h; Title compound not separated from byproducts.;
DOI:10.1002/anie.200700841

Reference yield:

: 91076-08-3
bis(dimethylphenylsilyl)zinc

: 768392-43-4
(E)-diethyl (3-phenylbut-2-en-1-yl) phosphate

: 945684-77-5
(R)-(-)-3-(dimethylphenylsilyl)-3-phenyl-1-butene

: C₁₈H₂₂Si

Guidance literature:: bis(dimethylphenylsilyl)zinc; With ((2S,3S)-6-mesityl-2,3-diphenyl-2,3,5,6-tetrahydroimidazo[1,2-c]quinazolin-5-yl)copper(I)chloride; In diethyl ether; at -78 - 0 ℃; for 0.5h; Schlenk technique; Inert atmosphere;

(E)-diethyl (3-phenylbut-2-en-1-yl) phosphate; In diethyl ether; at 0 ℃; Overall yield = 39 mg; regioselective reaction; Schlenk technique; Inert atmosphere;
DOI:10.1002/chem.201501371

Reference yield:

: 768-33-2
phenyldimethylsilyl chloride

: 945684-77-5
(R)-(-)-3-(dimethylphenylsilyl)-3-phenyl-1-butene

: C₁₈H₂₂Si

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium / tetrahydrofuran / 4 h / 0 °C / Schlenk technique; Inert atmosphere

1.2: 0.5 h / 0 °C / Schlenk technique; Inert atmosphere

2.1: ((2S,3S)-6-mesityl-2,3-diphenyl-2,3,5,6-tetrahydroimidazo[1,2-c]quinazolin-5-yl)copper(I)chloride / diethyl ether / 0.5 h / -78 - 0 °C / Schlenk technique; Inert atmosphere

2.2: 0 °C / Schlenk technique; Inert atmosphere

With ((2S,3S)-6-mesityl-2,3-diphenyl-2,3,5,6-tetrahydroimidazo[1,2-c]quinazolin-5-yl)copper(I)chloride; lithium; In tetrahydrofuran; diethyl ether;
DOI:10.1002/chem.201501371