C₃₆H₄₄N₂O₆SSi

Base Information

• Chemical Name: C₃₆H₄₄N₂O₆SSi
• CAS No.: 221526-60-9
• Molecular Formula: C₃₆H₄₄N₂O₆SSi
• Molecular Weight: 660.907
• Mol file: 221526-60-9.mol

Synonyms:C₃₆H₄₄N₂O₆SSi

Chemical Property of C₃₆H₄₄N₂O₆SSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₆H₄₄N₂O₆SSi

There total 17 articles about C₃₆H₄₄N₂O₆SSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

C42H48N2O8S2Si (221526-59-6) → C36H44N2O6SSi (221526-60-9)

Guidance literature:

With sodium anthracenide; In 1,2-dimethoxyethane; at -65 ℃; for 2h;

DOI:10.1016/S0040-4039(98)80033-6

Reference yield:

1-Benzenesulfonyl-3,4,5,6-tetrahydropyridin-2-one (7744-25-4) → C36H44N2O6SSi (221526-60-9)

Guidance literature:

Multi-step reaction with 12 steps

1: 73 percent / LiN(TMS)2 / tetrahydrofuran / 11 h / -60 °C

2: LiN(TMS)2 / tetrahydrofuran / 2 h / -60 °C

3: n-Bu₃SnH, AIBN / benzene / 0.5 h / Heating

4: KN(TMS)2 / tetrahydrofuran / -30 °C

5: mCPBA / CH₂Cl₂

6: various solvent(s) / 20 h / 180 °C

7: PPTS / CH₂Cl₂

8: 21 percent / HCl / tetrahydrofuran / 2 h / Heating

9: HCl

10: imidazole / dimethylformamide / 2 h / Ambient temperature

11: p-TsOH / benzene / 2 h / Heating

12: 94 percent / sodium anthracenide / 1,2-dimethoxy-ethane / 2 h / -65 °C

With 1H-imidazole; hydrogenchloride; sodium anthracenide; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; pyridinium p-toluenesulfonate; potassium hexamethylsilazane; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; lithium hexamethyldisilazane; In tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane; N,N-dimethyl-formamide; benzene;

DOI:10.1016/S0040-4039(98)80033-6

Reference yield:

methyl N-benzenesulfonyl-L-serinate (221526-66-5) → C36H44N2O6SSi (221526-60-9)

Guidance literature:

Multi-step reaction with 14 steps

1: 90 percent / p-TsOH / benzene / 3 h / Ambient temperature

2: 92 percent / DIBAL-H / toluene / 2 h / -78 °C

3: 73 percent / LiN(TMS)2 / tetrahydrofuran / 11 h / -60 °C

4: LiN(TMS)2 / tetrahydrofuran / 2 h / -60 °C

5: n-Bu₃SnH, AIBN / benzene / 0.5 h / Heating

6: KN(TMS)2 / tetrahydrofuran / -30 °C

7: mCPBA / CH₂Cl₂

8: various solvent(s) / 20 h / 180 °C

9: PPTS / CH₂Cl₂

10: 21 percent / HCl / tetrahydrofuran / 2 h / Heating

11: HCl

12: imidazole / dimethylformamide / 2 h / Ambient temperature

13: p-TsOH / benzene / 2 h / Heating

14: 94 percent / sodium anthracenide / 1,2-dimethoxy-ethane / 2 h / -65 °C

With 1H-imidazole; hydrogenchloride; sodium anthracenide; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; pyridinium p-toluenesulfonate; potassium hexamethylsilazane; diisobutylaluminium hydride; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; lithium hexamethyldisilazane; In tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane; N,N-dimethyl-formamide; toluene; benzene;

DOI:10.1016/S0040-4039(98)80033-6

upstream raw materials:

C₄₂H₄₈N₂O₈S₂Si

1-Benzenesulfonyl-3,4,5,6-tetrahydropyridin-2-one

tert-butylchlorodiphenylsilane

methyl N-benzenesulfonyl-L-serinate

Downstream raw materials:

C₃₅H₄₈N₂O₆Si