2-Methyl-2-[(E)-2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethenyl]-1,3-diox olane

Base Information

• Chemical Name: 2-Methyl-2-[(E)-2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethenyl]-1,3-diox olane
• CAS No.: 14398-32-4
• Molecular Formula: C15H24 O2
• Molecular Weight: 236.354
• Hs Code.: 2932999099
• Mol file: 14398-32-4.mol

Synonyms:1,3-Dioxolane,2-methyl-2-[2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethenyl]-, (E)-; 1,3-Dioxolane,2-methyl-2-[2-(2,6,6-trimethyl-1-cyclohexen-1-yl)vinyl]-, (E)- (8CI); b-Ionone ethylene ketal

Chemical Property of 2-Methyl-2-[(E)-2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethenyl]-1,3-diox olane

Chemical Property:

• PSA: 18.46000
• LogP: 3.83220

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Methyl-2-[(E)-2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethenyl]-1,3-diox olane

There total 7 articles about 2-Methyl-2-[(E)-2-(2,6,6-trimethyl-1-cyclohexen-1-yl)ethenyl]-1,3-diox olane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

(E)-β-ionone (79-77-6,14901-07-6) + ethylene glycol (107-21-1) → (3E)-4-(2,6,6-trimethyl-1(2)-cyclohexenyl)-3-buten-2-one-ethylene acetal (14398-32-4)

Guidance literature:

With toluene-4-sulfonic acid; In Petroleum ether; for 120h; Heating;

Reference yield:

5-Azido-6-hydroxy-5,6-dihydro-β-jonon → (3E)-4-(2,6,6-trimethyl-1(2)-cyclohexenyl)-3-buten-2-one-ethylene acetal (14398-32-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 85 percent / p-toluenesulfonic acid / benzene / 12 h / Heating

2: 59 percent / P(OEt)3 / CH₂Cl₂ / 40 h / Heating

3: 98 percent / p-toluenesulfonic acid / diethyl ether; H₂O / 0.5 h / Ambient temperature

4: 43 percent / 1.) isopentylnitrite, triethylamine / 1.) 30 min; 2.) CCl₄, 80 deg C, 30 min

5: 75 percent / p-toluenesulfonic acid / benzene / 12 h / Heating

With toluene-4-sulfonic acid; triethylamine; triethyl phosphite; isopentyl nitrite; In diethyl ether; dichloromethane; water; benzene;

DOI:10.1002/hlca.19820650535

Reference yield:

5,6-epoxy-trans-β-ionone (36340-49-5) → (3E)-4-(2,6,6-trimethyl-1(2)-cyclohexenyl)-3-buten-2-one-ethylene acetal (14398-32-4)

Guidance literature:

Multi-step reaction with 6 steps

1: 41 percent / NaN₃, MgCl₂*6H₂O / methanol / 120 h / Heating

2: 85 percent / p-toluenesulfonic acid / benzene / 12 h / Heating

3: 59 percent / P(OEt)3 / CH₂Cl₂ / 40 h / Heating

4: 98 percent / p-toluenesulfonic acid / diethyl ether; H₂O / 0.5 h / Ambient temperature

5: 43 percent / 1.) isopentylnitrite, triethylamine / 1.) 30 min; 2.) CCl₄, 80 deg C, 30 min

6: 75 percent / p-toluenesulfonic acid / benzene / 12 h / Heating

With sodium azide; toluene-4-sulfonic acid; triethylamine; magnesium chloride; triethyl phosphite; isopentyl nitrite; In methanol; diethyl ether; dichloromethane; water; benzene;

DOI:10.1002/hlca.19820650535

upstream raw materials:

(E)-β-ionone

ethylene glycol

5,6-epoxy-trans-β-ionone

Downstream raw materials:

(E)-β-ionone