(2S,3R,4R,5S,6S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(iodomethyl)tetrahydro-2H-pyran-3,4,5-triol

Base Information

Chemical Name:(2S,3R,4R,5S,6S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(iodomethyl)tetrahydro-2H-pyran-3,4,5-triol
CAS No.:1219000-72-2
Molecular Formula:C₂₁H₂₄ClIO₅
Molecular Weight:518.776
Hs Code.:

Synonyms:(2S,3R,4R,5S,6S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(iodomethyl)tetrahydro-2H-pyran-3,4,5-triol

Suppliers and Price of (2S,3R,4R,5S,6S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(iodomethyl)tetrahydro-2H-pyran-3,4,5-triol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R,4R,5S,6S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(iodomethyl)tetrahydro-2H-pyran-3,4,5-triol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R,4R,5S,6S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(iodomethyl)tetrahydro-2H-pyran-3,4,5-triol

There total 2 articles about (2S,3R,4R,5S,6S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(iodomethyl)tetrahydro-2H-pyran-3,4,5-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 461432-26-8,1373321-04-0
dapagliflozin

: 1219000-72-2
(2S,3R,4R,5S,6S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(iodomethyl)tetrahydro-2H-pyran-3,4,5-triol

Guidance literature:: With 1H-imidazole; iodine; triphenylphosphine; In tetrahydrofuran; at 70 ℃;
DOI:10.1002/anie.202111993

Reference yield:

: (2S,3R,4R,5S,6R)-[2-chloro-3-(4-ethoxy-benzyl)phenyl]-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol

: 1219000-72-2
(2S,3R,4R,5S,6S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(iodomethyl)tetrahydro-2H-pyran-3,4,5-triol

Guidance literature:: With 1H-imidazole; iodine; triphenylphosphine; In dichloromethane; at 0 ℃; for 18h; Reflux;

Reference yield: 58.0%

: 1219000-72-2
(2S,3R,4R,5S,6S)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(iodomethyl)tetrahydro-2H-pyran-3,4,5-triol

: [bis(difluoromethyl)zinc(dmpu)₂]

: C₂₂H₂₅ClF₂O₅

Guidance literature:: With 2,2':6,2''-terpyridine; copper(II) bis(trifluoromethanesulfonate); (2,4,6-trimethylphenyl)diazonium tetrafluoronorate; In dimethyl sulfoxide; at 20 ℃; for 0.75h; Inert atmosphere; Sealed tube; Schlenk technique;
DOI:10.1002/anie.202111993