Technology Process of C16H22BrNO3S
There total 3 articles about C16H22BrNO3S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(2-allyl-1-benzenesulfonyl-3-bromo-piperidin-3-yl)-acetic acid ethyl ester;
With
diisobutylaluminium hydride;
In
tetrahydrofuran;
at 20 ℃;
for 5h;
Inert atmosphere;
Cooling with ice;
With
ammonium chloride;
In
tetrahydrofuran; water;
Inert atmosphere;
Saturated solution;
Cooling with ice;
DOI:10.1016/j.tet.2011.08.025
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: N-Bromosuccinimide; boron trifluoride diethyl etherate / dichloromethane / 5.08 h / 20 °C / Inert atmosphere; Cooling with ice
2.1: diisobutylaluminium hydride / tetrahydrofuran / 5 h / 20 °C / Inert atmosphere; Cooling with ice
2.2: Inert atmosphere; Saturated solution; Cooling with ice
With
N-Bromosuccinimide; boron trifluoride diethyl etherate; diisobutylaluminium hydride;
In
tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tet.2011.08.025
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 2 h / Inert atmosphere; Reflux
2.1: N-Bromosuccinimide; boron trifluoride diethyl etherate / dichloromethane / 5.08 h / 20 °C / Inert atmosphere; Cooling with ice
3.1: diisobutylaluminium hydride / tetrahydrofuran / 5 h / 20 °C / Inert atmosphere; Cooling with ice
3.2: Inert atmosphere; Saturated solution; Cooling with ice
With
N-Bromosuccinimide; boron trifluoride diethyl etherate; diisobutylaluminium hydride; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tet.2011.08.025
