Allyl-[1-(3-methoxy-phenyl)-bicyclo[3.3.1]non-9-yl]-amine; hydrochloride

Base Information

Chemical Name:Allyl-[1-(3-methoxy-phenyl)-bicyclo[3.3.1]non-9-yl]-amine; hydrochloride
CAS No.:75210-02-5
Molecular Formula:C₁₉H₂₇NO*ClH
Molecular Weight:321.89
Hs Code.:

Synonyms:Allyl-[1-(3-methoxy-phenyl)-bicyclo[3.3.1]non-9-yl]-amine; hydrochloride

Suppliers and Price of Allyl-[1-(3-methoxy-phenyl)-bicyclo[3.3.1]non-9-yl]-amine; hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of Allyl-[1-(3-methoxy-phenyl)-bicyclo[3.3.1]non-9-yl]-amine; hydrochloride

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of Allyl-[1-(3-methoxy-phenyl)-bicyclo[3.3.1]non-9-yl]-amine; hydrochloride

There total 10 articles about Allyl-[1-(3-methoxy-phenyl)-bicyclo[3.3.1]non-9-yl]-amine; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.4%

: 75209-51-7
9-amino-1-(m-methoxyphenyl)bicyclo<3.3.1>nonane

: 75210-02-5
Allyl-[1-(3-methoxy-phenyl)-bicyclo[3.3.1]non-9-yl]-amine; hydrochloride

Guidance literature:: With hydrogenchloride; sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 150 ℃;
DOI:10.1248/cpb.28.1022

Reference yield:

: 15547-89-4
2-(3-methoxyphenyl)cyclohexanone

: 75210-02-5
Allyl-[1-(3-methoxy-phenyl)-bicyclo[3.3.1]non-9-yl]-amine; hydrochloride

Guidance literature:: Multi-step reaction with 9 steps

1: 80.2 percent / TsOH / toluene / 20 h / Heating

2: benzene / 18 h / Heating

3: 2N HCl / benzene / 3 h / Ambient temperature

4: 61.2 percent / TsOH / benzene / 75 h / Heating

5: 1.) hydrazine hydrate, conc. HCl, 2.) KOH / 1.) triethylene glycol, 130 deg C, 7 h, 2.) triethylene glycol, 210 deg C, 4 h

6: 580 mg / conc. HCl / ethanol; diethyl ether / 1.5 h / Ambient temperature

7: 85 percent / NH₂OH*HCl, NaOAc*3H₂O / ethanol / 1 h / Heating

8: 4.6 g / LiAlH₄ / tetrahydrofuran / 3 h / Heating

9: 59.4 percent / 1.) NaHCO₃, 2.) HCl / dimethylformamide / 150 °C

With hydrogenchloride; potassium hydroxide; lithium aluminium tetrahydride; hydroxylamine hydrochloride; sodium acetate; sodium hydrogencarbonate; toluene-4-sulfonic acid; hydrazine hydrate; In tetrahydrofuran; diethyl ether; ethanol; N,N-dimethyl-formamide; toluene; benzene;
DOI:10.1248/cpb.28.1022

Reference yield:

: 75209-39-1
morpholine enamine of 2-(m-methoxyphenyl)cyclohexanone

: 75210-02-5
Allyl-[1-(3-methoxy-phenyl)-bicyclo[3.3.1]non-9-yl]-amine; hydrochloride

Guidance literature:: Multi-step reaction with 8 steps

1: benzene / 18 h / Heating

2: 2N HCl / benzene / 3 h / Ambient temperature

3: 61.2 percent / TsOH / benzene / 75 h / Heating

4: 1.) hydrazine hydrate, conc. HCl, 2.) KOH / 1.) triethylene glycol, 130 deg C, 7 h, 2.) triethylene glycol, 210 deg C, 4 h

5: 580 mg / conc. HCl / ethanol; diethyl ether / 1.5 h / Ambient temperature

6: 85 percent / NH₂OH*HCl, NaOAc*3H₂O / ethanol / 1 h / Heating

7: 4.6 g / LiAlH₄ / tetrahydrofuran / 3 h / Heating

8: 59.4 percent / 1.) NaHCO₃, 2.) HCl / dimethylformamide / 150 °C

With hydrogenchloride; potassium hydroxide; lithium aluminium tetrahydride; hydroxylamine hydrochloride; sodium acetate; sodium hydrogencarbonate; toluene-4-sulfonic acid; hydrazine hydrate; In tetrahydrofuran; diethyl ether; ethanol; N,N-dimethyl-formamide; benzene;
DOI:10.1248/cpb.28.1022