5'-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-1'-oxo-spiro[piperidine-4,3'-1H-isoindole]

Base Information

Chemical Name:5'-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-1'-oxo-spiro[piperidine-4,3'-1H-isoindole]
CAS No.:1159094-15-1
Molecular Formula:C₃₀H₂₉N₃O₅
Molecular Weight:511.577
Hs Code.:

Synonyms:5'-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-1'-oxo-spiro[piperidine-4,3'-1H-isoindole]

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5'-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-1'-oxo-spiro[piperidine-4,3'-1H-isoindole]

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Technology Process of 5'-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-1'-oxo-spiro[piperidine-4,3'-1H-isoindole]

There total 1 articles about 5'-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-1'-oxo-spiro[piperidine-4,3'-1H-isoindole] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1159094-14-0
C₃₅H₃₅N₃O₇

: 1159094-15-1
5'-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-1'-oxo-spiro[piperidine-4,3'-1H-isoindole]

Guidance literature:: C₃₅H₃₅N₃O₇; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.75h;

With hydrogen; palladium 10% on activated carbon; In ethanol; for 36h; under 3345.86 Torr;

Reference yield: 100.0%

: 130423-83-5
5-(phenylethynyl)furan-2-carboxylic acid

: 1159094-15-1
5'-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-1'-oxo-spiro[piperidine-4,3'-1H-isoindole]

: 1159094-16-2
5'-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-1-(5-phenylethynyl-furan-2-yl)carbonyl-1'-oxo-spiro[piperidine-4,3'-1H-isoindole]

Guidance literature:: With bis-(2-oxo-3-oxazolidinyl)phosphoryl chloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 1.5h; Inert atmosphere;