1-{[4-(1,1-dimethylethyl)phenyl]methyl}-2-(phenylamino)-4,6(1H,5H)-pyrimidinedione

Base Information

Chemical Name:1-{[4-(1,1-dimethylethyl)phenyl]methyl}-2-(phenylamino)-4,6(1H,5H)-pyrimidinedione
CAS No.:1039764-34-5
Molecular Formula:C₂₁H₂₃N₃O₂
Molecular Weight:349.433
Hs Code.:

Synonyms:1-{[4-(1,1-dimethylethyl)phenyl]methyl}-2-(phenylamino)-4,6(1H,5H)-pyrimidinedione

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Chemical Property of 1-{[4-(1,1-dimethylethyl)phenyl]methyl}-2-(phenylamino)-4,6(1H,5H)-pyrimidinedione

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Technology Process of 1-{[4-(1,1-dimethylethyl)phenyl]methyl}-2-(phenylamino)-4,6(1H,5H)-pyrimidinedione

There total 3 articles about 1-{[4-(1,1-dimethylethyl)phenyl]methyl}-2-(phenylamino)-4,6(1H,5H)-pyrimidinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 1039764-33-4
N-{[4-(1,1-dimethylethyl)phenyl]methyl}-N'-phenylguanidine

: 105-53-3
diethyl malonate

: 1039764-34-5
1-{[4-(1,1-dimethylethyl)phenyl]methyl}-2-(phenylamino)-4,6(1H,5H)-pyrimidinedione

Guidance literature:: With sodium ethanolate; In ethanol; 2-methoxy-ethanol; for 24h; Heating / reflux;

Reference yield:

: 39895-55-1
4-(1,1-dimethylethyl)-benzenemethanamine

: 1039764-34-5
1-{[4-(1,1-dimethylethyl)phenyl]methyl}-2-(phenylamino)-4,6(1H,5H)-pyrimidinedione

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol

2: sodium ethanolate / ethanol; 2-methoxy-ethanol / 24 h / Heating / reflux

With sodium ethanolate; In ethanol; 2-methoxy-ethanol;

Reference yield:

: 27806-84-4
S-methyl-N-phenylisothiourea hydroiodide

: 1039764-34-5
1-{[4-(1,1-dimethylethyl)phenyl]methyl}-2-(phenylamino)-4,6(1H,5H)-pyrimidinedione

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol

2: sodium ethanolate / ethanol; 2-methoxy-ethanol / 24 h / Heating / reflux

With sodium ethanolate; In ethanol; 2-methoxy-ethanol;