10-(4-Methylphenylsulfonyl)-1,7-dioxa-4-thia-10-azacyclododecane

Base Information

• Chemical Name: 10-(4-Methylphenylsulfonyl)-1,7-dioxa-4-thia-10-azacyclododecane
• CAS No.: 146945-09-7
• Molecular Formula: C₁₅H₂₃NO₄S₂
• Molecular Weight: 345.484
• Mol file: 146945-09-7.mol

Synonyms:10-(4-Methylphenylsulfonyl)-1,7-dioxa-4-thia-10-azacyclododecane

Chemical Property of 10-(4-Methylphenylsulfonyl)-1,7-dioxa-4-thia-10-azacyclododecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 10-(4-Methylphenylsulfonyl)-1,7-dioxa-4-thia-10-azacyclododecane

There total 2 articles about 10-(4-Methylphenylsulfonyl)-1,7-dioxa-4-thia-10-azacyclododecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

N,N-bis<2-<2-<(p-tolylsulfonyl)oxy>ethoxy>ethyl>-p-toluenesulfonamide (118187-55-6) → 10-(4-Methylphenylsulfonyl)-1,7-dioxa-4-thia-10-azacyclododecane (146945-09-7)

Guidance literature:

With disodium 1,2-ethanedithiolate; In N,N-dimethyl-formamide; at 90 ℃; for 2.5h;

DOI:10.1039/DT9930000625

Reference yield:

2,2'-((azanediylbis(ethane-2,1-diyl))bis(oxy))diethanol (54384-47-3) → 10-(4-Methylphenylsulfonyl)-1,7-dioxa-4-thia-10-azacyclododecane (146945-09-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / pyridine / 2.5 h / -5 °C

2: 75 percent / ethane-1,2-thiol disodium salt / dimethylformamide / 2.5 h / 90 °C

With pyridine; disodium 1,2-ethanedithiolate; In N,N-dimethyl-formamide;

DOI:10.1039/DT9930000625

upstream raw materials:

N,N-bis<2-<2-<(p-tolylsulfonyl)oxy>ethoxy>ethyl>-p-toluenesulfonamide

2,2'-((azanediylbis(ethane-2,1-diyl))bis(oxy))diethanol