Ethanone, 1-[(1R,2R)-2-phenylcyclopropyl]-, rel- (9CI)

Base Information

Chemical Name:Ethanone, 1-[(1R,2R)-2-phenylcyclopropyl]-, rel- (9CI)
CAS No.:14063-86-6
Molecular Formula:C₁₁H₁₂O
Molecular Weight:160.216
Hs Code.:
Mol file:14063-86-6.mol

Synonyms:Ethanone,1-(2-phenylcyclopropyl)-, trans-; Ketone, methyl 2-phenylcyclopropyl, trans-(8CI); trans-1-Acetyl-2-phenylcyclopropane; trans-2-Phenylcyclopropyl methylketone

Suppliers and Price of Ethanone, 1-[(1R,2R)-2-phenylcyclopropyl]-, rel- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Ethanone, 1-[(1R,2R)-2-phenylcyclopropyl]-, rel- (9CI)

Chemical Property:

PSA：17.07000
LogP:2.37910

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Ethanone, 1-[(1R,2R)-2-phenylcyclopropyl]-, rel- (9CI)

There total 6 articles about Ethanone, 1-[(1R,2R)-2-phenylcyclopropyl]-, rel- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: (1R,2S)-N-methoxy-N-methyl-2-phenylcyclopropanecarboxamide

: 75-16-1
methylmagnesium bromide

: 827-92-9,14063-86-6,17597-82-9
1-((1R,2S)-2-phenylcyclopropyl)ethanone

Guidance literature:: (1R,2S)-N-methoxy-N-methyl-2-phenylcyclopropanecarboxamide; methylmagnesium bromide; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

With ammonium chloride; In tetrahydrofuran; water; Inert atmosphere;
DOI:10.1016/j.bmc.2013.08.036

Reference yield: 85.0%

: (1S,2R)-N-methoxy-N-methyl-2-phenylcyclopropanecarboxamide

: 75-16-1
methylmagnesium bromide

: 827-92-9,14063-86-6,17597-82-9
1-((1S,2R)-2-phenylcyclopropyl)ethanone

Guidance literature:: (1S,2R)-N-methoxy-N-methyl-2-phenylcyclopropanecarboxamide; methylmagnesium bromide; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

With ammonium chloride; In tetrahydrofuran; water; Inert atmosphere;
DOI:10.1016/j.bmc.2013.08.036

Reference yield:

: 23020-18-0
(1S,2R)-2-phenylcyclopropanecarboxylic acid

: 827-92-9,14063-86-6,17597-82-9
1-((1S,2R)-2-phenylcyclopropyl)ethanone

Guidance literature:: Multi-step reaction with 2 steps

1.1: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 1 h / 20 °C

1.2: 1.5 h / 20 °C

2.1: tetrahydrofuran / 0 - 20 °C / Inert atmosphere

2.2: Inert atmosphere

With oxalyl dichloride; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmc.2013.08.036