BETA-OXO-2,4-DICHLORO-BENZENEPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER

Base Information

Chemical Name:BETA-OXO-2,4-DICHLORO-BENZENEPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER
CAS No.:952019-71-5
Molecular Formula:C₁₃H₁₄Cl₂O₃
Molecular Weight:289.158
Hs Code.:
Mol file:952019-71-5.mol

Synonyms:3-(2,4-dichlorophenyl)-3-oxopropionic acid tert-butyl ester

Suppliers and Price of BETA-OXO-2,4-DICHLORO-BENZENEPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of BETA-OXO-2,4-DICHLORO-BENZENEPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of BETA-OXO-2,4-DICHLORO-BENZENEPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER

There total 2 articles about BETA-OXO-2,4-DICHLORO-BENZENEPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 646528-36-1
N-methoxy-N-methyl-2,4-dichlorobenzamide

: 540-88-5
acetic acid tert-butyl ester

: 952019-71-5
3-(2,4-dichlorophenyl)-3-oxopropionic acid tert-butyl ester

Guidance literature:: acetic acid tert-butyl ester; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.25h;

N-methoxy-N-methyl-2,4-dichlorobenzamide; In tetrahydrofuran; at -78 - 20 ℃; for 4h; Further stages.;
DOI:10.1080/00397910701481237

Reference yield:

: 89-75-8
2,4-dichlorobenzoyl chloride

: 952019-71-5
3-(2,4-dichlorophenyl)-3-oxopropionic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: pyridine / CH₂Cl₂

2.1: LDA / tetrahydrofuran / 0.25 h / -78 °C

2.2: 89 percent / tetrahydrofuran / 4 h / -78 - 20 °C

With pyridine; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;
DOI:10.1080/00397910701481237

Reference yield: 25.0%

: 105-36-2
ethyl bromoacetate

: 952019-71-5
3-(2,4-dichlorophenyl)-3-oxopropionic acid tert-butyl ester

: 952019-73-7
2-acetyl-3-(2,4-dichlorobenzoyl)succinic acid 4-tert-butyl ester 1-ethyl ester

Guidance literature:: 3-(2,4-dichlorophenyl)-3-oxopropionic acid tert-butyl ester; With sodium ethanolate; In ethanol; for 0.166667h;

ethyl bromoacetate; In ethanol; toluene; at 20 ℃; for 7h; Further stages.;
DOI:10.1080/00397910701481237