propan-2-yl 3-({4-[3-(tert-butylamino)propyl]phenyl}carbonyl)-2-ethylindolizine-7-carboxylate

Base Information

Chemical Name:propan-2-yl 3-({4-[3-(tert-butylamino)propyl]phenyl}carbonyl)-2-ethylindolizine-7-carboxylate
CAS No.:1376437-32-9
Molecular Formula:C₂₈H₃₆N₂O₃
Molecular Weight:448.605
Hs Code.:

Synonyms:propan-2-yl 3-({4-[3-(tert-butylamino)propyl]phenyl}carbonyl)-2-ethylindolizine-7-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of propan-2-yl 3-({4-[3-(tert-butylamino)propyl]phenyl}carbonyl)-2-ethylindolizine-7-carboxylate

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Technology Process of propan-2-yl 3-({4-[3-(tert-butylamino)propyl]phenyl}carbonyl)-2-ethylindolizine-7-carboxylate

There total 3 articles about propan-2-yl 3-({4-[3-(tert-butylamino)propyl]phenyl}carbonyl)-2-ethylindolizine-7-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 1376437-15-8
propan-2-yl 3-{[4-(4-chlorobutyl)phenyl]carbonyl}-2-ethylindolizine-7-carboxylate

: 75-64-9
tert-butylamine

: 1376437-32-9
propan-2-yl 3-({4-[3-(tert-butylamino)propyl]phenyl}carbonyl)-2-ethylindolizine-7-carboxylate

Guidance literature:: With potassium iodide; In acetonitrile; at 105 ℃; for 48h; Sealed tube;

Reference yield:

: 1376436-91-7
propan-2-yl 2-ethylindolizine-7-carboxylate

: 1376437-32-9
propan-2-yl 3-({4-[3-(tert-butylamino)propyl]phenyl}carbonyl)-2-ethylindolizine-7-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 4.5 h / 85 °C

2: potassium iodide / acetonitrile / 48 h / 105 °C / Sealed tube

With N-ethyl-N,N-diisopropylamine; potassium iodide; In tetrahydrofuran; acetonitrile;

Reference yield:

: 401928-62-9
4-(4-chlorobutyl)benzoyl chloride

: 1376437-32-9
propan-2-yl 3-({4-[3-(tert-butylamino)propyl]phenyl}carbonyl)-2-ethylindolizine-7-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 4.5 h / 85 °C

2: potassium iodide / acetonitrile / 48 h / 105 °C / Sealed tube

With N-ethyl-N,N-diisopropylamine; potassium iodide; In tetrahydrofuran; acetonitrile;