Phenethylamine, a-(bromomethyl)-, hydrobromide

Base Information

• Chemical Name: Phenethylamine, a-(bromomethyl)-, hydrobromide
• CAS No.: 13892-90-5
• Molecular Formula: BrH*C₉H₁₂BrN
• Molecular Weight: 295.017
• Hs Code.: 2921499090
• Mol file: 13892-90-5.mol

Synonyms:Benzeneethanamine,a-(bromomethyl)-, hydrobromide(9CI); Phenethylamine, a-(bromomethyl)-, hydrobromide (8CI)

Chemical Property of Phenethylamine, a-(bromomethyl)-, hydrobromide

Chemical Property:

• Vapor Pressure: 0.000967mmHg at 25°C
• Boiling Point: 295.5°Cat760mmHg
• Flash Point: 132.5°C
• PSA: 26.02000
• Density: g/cm³
• LogP: 3.60970

Purity/Quality:

ALPHA-(BROMOMETHYL)-PHENETHYLAMINE HYDROBROMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phenethylamine, a-(bromomethyl)-, hydrobromide

There total 2 articles about Phenethylamine, a-(bromomethyl)-, hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Phenylalanine (150-30-1,25191-15-5,658-69-5,67675-33-6) → 1-bromomethyl-2-phenyl-ethylamine; hydrobromide (13892-90-5,283589-06-0)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / tetrahydrofuran / Heating

2: SOBr₂

With lithium aluminium tetrahydride; sulfurous dibromide; In tetrahydrofuran;

DOI:10.1002/hlca.200490021

Reference yield:

rac-phenylalaninol (1795-98-8,3182-95-4,5267-64-1,16088-07-6) → 1-bromomethyl-2-phenyl-ethylamine; hydrobromide (13892-90-5,283589-06-0)

Guidance literature:

With sulfurous dibromide;

DOI:10.1002/hlca.200490021

Reference yield:

carbon disulfide (75-15-0,12122-00-8) + 1-bromomethyl-2-phenyl-ethylamine; hydrobromide (13892-90-5,283589-06-0) → (4S)-4-benzyl-1,3-thiazolidine-2-thione (13897-15-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1021/jm00324a027

upstream raw materials:

rac-phenylalaninol

Phenylalanine

Downstream raw materials:

(4S)-4-benzyl-1,3-thiazolidine-2-thione

Thiosulfuric acid S-(2-amino-3-phenyl-propyl) ester

1-(2-amino-3-phenyl-propyldisulfanylmethyl)-2-phenyl-ethylamine

3-benzyl-[1,2]thiazetidine 1,1-dioxide

Refernces