2-[4-amino-3-bromo-5-(2,2,2-trifluoroethoxy)phenyl]-3-cyclobutylpropionic acid methyl ester

Base Information

Chemical Name:2-[4-amino-3-bromo-5-(2,2,2-trifluoroethoxy)phenyl]-3-cyclobutylpropionic acid methyl ester
CAS No.:1168134-09-5
Molecular Formula:C₁₆H₁₉BrF₃NO₃
Molecular Weight:410.231
Hs Code.:

Synonyms:2-[4-amino-3-bromo-5-(2,2,2-trifluoroethoxy)phenyl]-3-cyclobutylpropionic acid methyl ester

Suppliers and Price of 2-[4-amino-3-bromo-5-(2,2,2-trifluoroethoxy)phenyl]-3-cyclobutylpropionic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[4-amino-3-bromo-5-(2,2,2-trifluoroethoxy)phenyl]-3-cyclobutylpropionic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[4-amino-3-bromo-5-(2,2,2-trifluoroethoxy)phenyl]-3-cyclobutylpropionic acid methyl ester

There total 6 articles about 2-[4-amino-3-bromo-5-(2,2,2-trifluoroethoxy)phenyl]-3-cyclobutylpropionic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1168134-08-4
2-[4-amino-3-(2,2,2-trifluoroethoxy)phenyl]-3-cyclobutylpropionic acid methyl ester

: 1168134-09-5
2-[4-amino-3-bromo-5-(2,2,2-trifluoroethoxy)phenyl]-3-cyclobutylpropionic acid methyl ester

Guidance literature:: With N-Bromosuccinimide; In chloroform; at 25 ℃; for 16h;

Reference yield:

: 1168134-05-1
2-[4-nitro-3-(2,2,2-trifluoroethoxy)phenyl]acetic acid

: 1168134-09-5
2-[4-amino-3-bromo-5-(2,2,2-trifluoroethoxy)phenyl]-3-cyclobutylpropionic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: sulfuric acid / 20 °C

2: potassium hydroxide / dimethyl sulfoxide / 16 h / 40 °C

3: hydrogen; palladium 10% on activated carbon / ethanol / 16 h / 25 °C / 2585.81 Torr

4: N-Bromosuccinimide / chloroform / 16 h / 25 °C

With N-Bromosuccinimide; sulfuric acid; palladium 10% on activated carbon; hydrogen; potassium hydroxide; In ethanol; chloroform; dimethyl sulfoxide;

Reference yield:

: 1168134-06-2
[4-nitro-3-(2,2,2-trifluoroethoxy)phenyl]acetic acid methyl ester

: 1168134-09-5
2-[4-amino-3-bromo-5-(2,2,2-trifluoroethoxy)phenyl]-3-cyclobutylpropionic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: potassium hydroxide / dimethyl sulfoxide / 16 h / 40 °C

2: hydrogen; palladium 10% on activated carbon / ethanol / 16 h / 25 °C / 2585.81 Torr

3: N-Bromosuccinimide / chloroform / 16 h / 25 °C

With N-Bromosuccinimide; palladium 10% on activated carbon; hydrogen; potassium hydroxide; In ethanol; chloroform; dimethyl sulfoxide;