[2-(4-methoxybenzyl)-8-methyl-3-oxo-1,2,3,4-tetrahydroisoquinolin-1-yl]acetonitrile

Base Information

Chemical Name:[2-(4-methoxybenzyl)-8-methyl-3-oxo-1,2,3,4-tetrahydroisoquinolin-1-yl]acetonitrile
CAS No.:1180656-62-5
Molecular Formula:C₂₀H₂₀N₂O₂
Molecular Weight:320.391
Hs Code.:

Synonyms:[2-(4-methoxybenzyl)-8-methyl-3-oxo-1,2,3,4-tetrahydroisoquinolin-1-yl]acetonitrile

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [2-(4-methoxybenzyl)-8-methyl-3-oxo-1,2,3,4-tetrahydroisoquinolin-1-yl]acetonitrile

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Technology Process of [2-(4-methoxybenzyl)-8-methyl-3-oxo-1,2,3,4-tetrahydroisoquinolin-1-yl]acetonitrile

There total 1 articles about [2-(4-methoxybenzyl)-8-methyl-3-oxo-1,2,3,4-tetrahydroisoquinolin-1-yl]acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 615-37-2
ortho-methylphenyl iodide

: 107-13-1,25014-41-9
acrylonitrile

: 81494-05-5
2-chloro-N-(4-methoxybenzyl)acetamide

: 1180656-62-5
[2-(4-methoxybenzyl)-8-methyl-3-oxo-1,2,3,4-tetrahydroisoquinolin-1-yl]acetonitrile

Guidance literature:: With norborn-2-ene; trifuran-2-yl-phosphane; water; palladium diacetate; caesium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 6h; Inert atmosphere;
DOI:10.1002/ejoc.200900255