C₄₃H₃₁F₆N₅O₂

Base Information

• Chemical Name: C₄₃H₃₁F₆N₅O₂
• CAS No.: 1394853-43-0
• Molecular Formula: C₄₃H₃₁F₆N₅O₂
• Molecular Weight: 763.742
• Mol file: 1394853-43-0.mol

Synonyms:C₄₃H₃₁F₆N₅O₂

Chemical Property of C₄₃H₃₁F₆N₅O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₃H₃₁F₆N₅O₂

There total 3 articles about C₄₃H₃₁F₆N₅O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-(4,5-bis(4-(4-nitro-2-(trifluoromethyl)phenoxy)phenyl)-1H-imidazol-2-yl)-9-ethylcarbazole (1394853-38-3) → C43H31F6N5O2 (1394853-43-0)

Guidance literature:

With ethanol; palladium on activated charcoal; hydrazine hydrate; for 8h; Reflux;

DOI:10.1016/j.jfluchem.2012.06.011

Reference yield:

1,2-bis(4-methoxyphenyl)-1,2-ethanedione (1226-42-2) → C43H31F6N5O2 (1394853-43-0)

Guidance literature:

Multi-step reaction with 4 steps

1: hydrogen bromide; acetic acid / water / 24 h / Reflux

2: potassium carbonate / 6.5 h / 20 - 110 °C

3: ammonium acetate; acetic acid / 14 h / Inert atmosphere; Reflux

4: ethanol; palladium on activated charcoal; hydrazine hydrate / 8 h / Reflux

With ethanol; palladium on activated charcoal; ammonium acetate; hydrogen bromide; potassium carbonate; hydrazine hydrate; acetic acid; In water;

DOI:10.1016/j.jfluchem.2012.06.011

Reference yield:

4,4'-dihydroxybenzil (33288-79-8) → C43H31F6N5O2 (1394853-43-0)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / 6.5 h / 20 - 110 °C

2: ammonium acetate; acetic acid / 14 h / Inert atmosphere; Reflux

3: ethanol; palladium on activated charcoal; hydrazine hydrate / 8 h / Reflux

With ethanol; palladium on activated charcoal; ammonium acetate; potassium carbonate; hydrazine hydrate; acetic acid;

DOI:10.1016/j.jfluchem.2012.06.011

upstream raw materials:

4,4'-dihydroxybenzil

2-(4,5-bis(4-(4-nitro-2-(trifluoromethyl)phenoxy)phenyl)-1H-imidazol-2-yl)-9-ethylcarbazole

1,2-bis(4-methoxyphenyl)-1,2-ethanedione