Cyclopentanol,3-amino-(7CI,8CI,9CI)

Base Information

• Chemical Name: Cyclopentanol,3-amino-(7CI,8CI,9CI)
• CAS No.: 13725-38-7
• Molecular Formula: C5H11 N O
• Molecular Weight: 101.15
• Hs Code.: 2922199090
• Mol file: 13725-38-7.mol

Synonyms:Cyclopentanol,3-amino-(7CI,8CI,9CI)

Chemical Property of Cyclopentanol,3-amino-(7CI,8CI,9CI)

Chemical Property:

• Boiling Point: 179.4±33.0 °C(Predicted)
• PKA: 15.06±0.40(Predicted)
• PSA: 46.25000
• Density: 1.084±0.06 g/cm3(Predicted)
• LogP: 0.55880
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

99% ^*data from raw suppliers

3-Aminocyclopentanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-Aminocyclopentanol (cas# 13725-38-7) can be used to modify acidic polymers for golf balls. It can be used as diesel fuel and gasoline detergents.

Technology Process of Cyclopentanol,3-amino-(7CI,8CI,9CI)

There total 6 articles about Cyclopentanol,3-amino-(7CI,8CI,9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trans-(+/-)-(3-hydroxycyclopentyl)-carbamic acid,1,1-dimethylethyl ester (1154870-59-3,207729-04-2) → 3-aminocyclopentan-1-ol (13725-38-7,167298-58-0)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 0 ℃; for 1h;

Reference yield:

tert-butyl N-(3-oxocyclopentyl)carbamate (847416-99-3) → 3-aminocyclopentan-1-ol (13725-38-7,167298-58-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol / 1 h / 0 - 20 °C

2: hydrogenchloride / 1,4-dioxane; dichloromethane / 1 h / 0 °C

With hydrogenchloride; sodium tetrahydroborate; In 1,4-dioxane; methanol; dichloromethane;

Reference yield:

3-azido-cyclopentan-1-one → 3-aminocyclopentan-1-ol (13725-38-7,167298-58-0)

Guidance literature:

Multi-step reaction with 3 steps

1: palladium 10% on activated carbon; hydrogen / acetic acid / 20 °C / 724.03 Torr / Inert atmosphere

2: sodium tetrahydroborate / methanol / 1 h / 0 - 20 °C

3: hydrogenchloride / 1,4-dioxane; dichloromethane / 1 h / 0 °C

With hydrogenchloride; sodium tetrahydroborate; palladium 10% on activated carbon; hydrogen; In 1,4-dioxane; methanol; dichloromethane; acetic acid;

upstream raw materials:

cyclopent-2-enone

tert-butyl N-(3-oxocyclopentyl)carbamate

trans-(+/-)-(3-hydroxycyclopentyl)-carbamic acid,1,1-dimethylethyl ester

Downstream raw materials:

tert-butyl N-(3-oxocyclopentyl)carbamate

trans-(+/-)-(3-hydroxycyclopentyl)-carbamic acid,1,1-dimethylethyl ester

Refernces

• 1、 -. "HETEROARYL SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE MODULATORS". . . Retrieved 2019/03/15.
• 2、 -. "Conjugated diene derivatives". . . Retrieved 2008/06/13.