847416-99-3

Basic information

• Product Name: INDEX NAME NOT YET ASSIGNED
• Synonyms: 3-(Boc-aMino)cyclopentanone;ML213;(3-Oxo-cyclopentyl)-carbamic acid tert-butyl ester;1-(Boc-amino)-3-oxocyclopentane
• CAS NO: 847416-99-3
• Molecular Formula: C₁₀H₁₇NO₃
• Molecular Weight: 199.25
• Product Categories: CYCLOPENTANE
• Mol File: 847416-99-3.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 319.2±31.0 °C(Predicted)
• Appearance: /
• Density: 1.07±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 11.89±0.20(Predicted)
• CAS DataBase Reference: INDEX NAME NOT YET ASSIGNED(CAS DataBase Reference)
• NIST Chemistry Reference: INDEX NAME NOT YET ASSIGNED(847416-99-3)
• EPA Substance Registry System: INDEX NAME NOT YET ASSIGNED(847416-99-3)

Safety Data

• Hazardous Substances Data: 847416-99-3(Hazardous Substances Data)

Upstream product

• 855863-93-3 3-tert-butoxycarbonylaminocyclopentanecarboxylic acid 
• 930-30-3 cyclopent-2-enone 
• 13725-38-7 3-aminocyclopentan-1-ol 
• 1154870-59-3 trans-(+/-)-(3-hydroxycyclopentyl)-carbamic acid,1,1-dimethylethyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 4248-19-5 tert-butyl carbazate 
• 1228748-71-7 3-amino cyclopentanone 

Downstream Products

• 1154870-59-3 trans-(+/-)-(3-hydroxycyclopentyl)-carbamic acid,1,1-dimethylethyl ester 
• 13725-38-7 3-aminocyclopentan-1-ol 
• 1408075-75-1 3-amino-1-methylcyclopentanol 
• 1197398-99-4 tert-butyl (3-aminocyclopentyl)carbamate 
• 1643574-07-5 tert-butyl N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopent-3-en-1-yl]carbamate 
• 946593-67-5 (1S,3S)-3-aminocyclopentan-1-ol 
• 1154870-59-3 (±)-trans-(3-hydroxycyclopentyl)carbamic acid tert-butyl ester 
• 1154870-59-3 (+/-)-cis-(3-hydroxy-cyclopentyl)-carbamic acid tert-butyl ester 
• 1215071-23-0 tert-butyl (3,3-difluorocyclopentyl)carbamate 
• 154737-89-0 tert-butyl ((1S,3S)-3-hydroxycyclopentyl)carbamate 
• 1154870-59-3 (+/-)-tert-butyl (cis-3-hydroxycyclopentyl)carbamate 
• 939398-48-8 3,3-difluorocyclopentan-1-amine hydrochloride 

Relevant articles and documents

Decarboxylative Oxygenation via Photoredox Catalysis

The direct conversion of aliphatic carboxylic acids to their dehomologated carbonyl analogues has been accomplished through photocatalytic decarboxylative oxygenation. This transformation is applicable to an array of carboxylic acid motifs, producing ketones, aldehydes, and amides in excellent yields. Preliminary results demonstrate that this methodology is further amenable to aldehyde substrates via in situ oxidation to the corresponding acid and subsequent decarboxylative oxygenation. We have exploited this strategy for the sequential oxidative dehomologation of linear aliphatic chains.

ANTIBACTERIAL COMPOUNDS HAVING BROAD SPECTRUM OF ACTIVITY

The present invention relates to novel antibacterial compounds, pharmaceutical compositions containing them and their use as antimicrobials.

SUBSTITUTED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF

The present disclosure relates to pyrimidine compounds of formula (I), their stereoisomers, tautomers, pharmaceutically acceptable salts, polymorphs, solvates, and hydrates thereof. The present disclosure also relates to process of preparation of these pyrimidine compounds, and to pharmaceutical compositions containing them. The compounds of the present disclosure are useful in the treatment, prevention or suppression of diseases and disorders mediated by epidermal growth factor receptor (EGFR) family kinases.