(2-OXO-CYCLOHEXYL)-ACETIC ACID METHYL ESTER

Base Information

• Chemical Name: (2-OXO-CYCLOHEXYL)-ACETIC ACID METHYL ESTER
• CAS No.: 13672-64-5
• Molecular Formula: C9H14 O3
• Molecular Weight: 170.208
• Hs Code.: 2918300090
• Mol file: 13672-64-5.mol

Synonyms:2-(Methoxycarbonylmethyl)cyclohexanone;2-Oxocyclohexaneacetic acid methyl ester; Methyl (2-oxocyclohexyl)acetate; Methyl2-oxocyclohexaneacetate

Chemical Property of (2-OXO-CYCLOHEXYL)-ACETIC ACID METHYL ESTER

Chemical Property:

• PSA: 43.37000
• LogP: 1.30880
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

methyl2-(2-oxocyclohexyl)acetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2-OXO-CYCLOHEXYL)-ACETIC ACID METHYL ESTER

There total 24 articles about (2-OXO-CYCLOHEXYL)-ACETIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1-(Trimethylsiloxy)bicyclo<4.1.0>heptan-7-carbonsaeure-methylester (79646-62-1) → methyl (2-oxocyclohexyl)acetate (13672-64-5)

Guidance literature:

With triethylammonium dihydrofluoride; In tetrahydrofuran; for 1h; Ambient temperature;

Reference yield: 91.0%

methyl 2-(2-oxocyclohexyl)-2-(phenylthio)acetate (85920-93-0) → methyl (2-oxocyclohexyl)acetate (13672-64-5)

Guidance literature:

With hydrogen; nickel;

DOI:10.1016/S0040-4039(00)81397-0

Reference yield: 90.0%

1-tri(n-butyl)stannyloxy-1-cyclohexene (17851-97-7) + bromoacetic acid methyl ester (96-32-2) → methyl (2-oxocyclohexyl)acetate (13672-64-5)

Guidance literature:

With air; triethyl borane; In hexane; at 20 ℃; for 9h;

DOI:10.1021/ol016268s

upstream raw materials:

methyl β-diazopropionate

cyclopentanone

1-(cyclohex-1-en-1-yl)piperidine

bromoacetic acid methyl ester

Downstream raw materials:

((1R,2S)-2-Hydroxy-cyclohexyl)-acetic acid methyl ester

((1S,2S)-2-Hydroxy-cyclohexyl)-acetic acid methyl ester

methyl (S)-(-)-(2-oxocycloxehyl)acetate

C₂₂H₂₀⁽²⁾H₃NO