1-(Cyclohex-1-en-1-yl)piperidine

Base Information

• Chemical Name: 1-(Cyclohex-1-en-1-yl)piperidine
• CAS No.: 2981-10-4
• Molecular Formula: C11H19 N
• Molecular Weight: 165.279
• Hs Code.: 29333999
• European Community (EC) Number: 622-974-1
• UNII: EV49787M4Y
• DSSTox Substance ID: DTXSID70952249
• Nikkaji Number: J50.655I
• Wikidata: Q72500499
• Mol file: 2981-10-4.mol

Synonyms:2981-10-4;1-(1-piperidino)cyclohexene;1-(Cyclohex-1-en-1-yl)piperidine;1-(cyclohexen-1-yl)piperidine;1-(1-Cyclohexen-1-yl)piperidine;1-(1-Cyclohexenyl)piperidine;Cyclohexenylpiperidine;1-Piperidinocyclohexene;PIPERIDINE, 1-(1-CYCLOHEXEN-1-YL)-;1-Piperidino-1-cyclohexene;N-(1-Cyclohexenyl)piperidine;1-Piperidinylcyclohexene;N-(1-Cyclohexen-1-yl)piperidine;BRN 0113990;1-(Cyclohex-1-enyl)piperidine;1-Piperidine, 1-(cyclohexenyl)-;56361-81-0;1-(1-Piperidinyl)cyclohexene;Piperidine, 1-(cyclohexenyl)-;1-cyclohexenylpiperidine;1-Cyclohexen-1-ylpiperidine;1-Cyclohex-1-enyl-piperidine;SCHEMBL497507;DTXSID70952249;1-(1-Piperidinyl)cyclohex-1-ene;EV49787M4Y;CAA98110;MFCD00014643;AKOS015897876;SB41090;1-(1-Cyclohexen-1-yl)piperidine, 97%;AS-40164;LS-114891;CS-0450683;FT-0658067;5-20-02-00048 (Beilstein Handbook Reference);A820059

Chemical Property of 1-(Cyclohex-1-en-1-yl)piperidine

Chemical Property:

• Appearance/Colour: Clear yellow liquid
• Vapor Pressure: 0.011mmHg at 25°C
• Refractive Index: 1.5140
• Boiling Point: 262.2oCat760mmHg
• PKA: 8.88±0.20(Predicted)
• Flash Point: 102.8oC
• PSA: 3.24000
• Density: 0.978g/cm³
• LogP: 2.86810
• Storage Temp.: Refrigerator (+4°C)
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 165.151749610
• Heavy Atom Count: 12
• Complexity: 166

Purity/Quality:

99% ^*data from raw suppliers

1-(1-Piperidino)cyclohexene 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R22:Harmful if swallowed.; R36/38:Irritating to eyes and skin.
• Hazard Codes: R22:Harmful if swallowed.; R36/38:Irritating to eyes and skin.
• Statements: 22-36/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CCN(CC1)C2=CCCCC2

Technology Process of 1-(Cyclohex-1-en-1-yl)piperidine

There total 5 articles about 1-(Cyclohex-1-en-1-yl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

piperidine (110-89-4) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → 1-(cyclohex-1-en-1-yl)piperidine (2981-10-4)

Guidance literature:

With Montmorillonite K 10 clay; for 0.133333h; microwave (160 Watts) irradiation;

DOI:10.1016/S0040-4039(97)00261-X

Reference yield:

piperidine (110-89-4) + cyclohexene (110-83-8) → 1-(cyclohex-1-en-1-yl)piperidine (2981-10-4)

Guidance literature:

With toluene-4-sulfonic acid; In benzene;

DOI:10.1016/j.mencom.2009.11.014

Reference yield:

lithium piperidide (4442-11-9) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → 1-(cyclohex-1-en-1-yl)piperidine (2981-10-4)

Guidance literature:

With tin(ll) chloride; Yield given. Multistep reaction; 1) Et₂O, r.t., 2 h, 2) r.t.;

DOI:10.1021/jo00045a009

upstream raw materials:

piperidine

cyclohexanone

lithium piperidide

cyclohexene

Downstream raw materials:

nitromethylcyclohexane

N-Formylpiperidine

cyclohexanone-2-propionitrile

N-cyclohexylidenebutylamine