Toluol-p-sulfonsaeure-2-phenyl-<1-¹⁴C>ethylester

Base Information

• Chemical Name: Toluol-p-sulfonsaeure-2-phenyl-<1-¹⁴C>ethylester
• CAS No.: 41936-78-1
• Molecular Formula: C₁₅H₁₆O₃S
• Molecular Weight: 278.345
• Mol file: 41936-78-1.mol

Synonyms:Toluol-p-sulfonsaeure-2-phenyl-<1-¹⁴C>ethylester

Chemical Property of Toluol-p-sulfonsaeure-2-phenyl-<1-¹⁴C>ethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Toluol-p-sulfonsaeure-2-phenyl-<1-¹⁴C>ethylester

There total 5 articles about Toluol-p-sulfonsaeure-2-phenyl-<1-¹⁴C>ethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-phenyl[1-14C]ethanol (4995-78-2) + p-toluenesulfonyl chloride (98-59-9) → Toluol-p-sulfonsaeure-2-phenyl-<1-14C>ethylester (41936-78-1)

Guidance literature:

2-phenyl[1-¹⁴C]ethanol; p-toluenesulfonyl chloride; With N,N'-dimethylbenzylamine; potassium carbonate; In water; at 20 - 25 ℃; for 1h;

With potassium hydroxide; In water; at 20 - 25 ℃; for 1h; pH=10;

With N,N-dimethylethylenediamine; In water; for 0.166667h;

DOI:10.1134/S1066362218010071

Reference yield:

benzyl chloride (100-44-7) → Toluol-p-sulfonsaeure-2-phenyl-<1-14C>ethylester (41936-78-1)

Guidance literature:

Multi-step reaction with 4 steps

1.1: water; ethanol / 6.75 h / Reflux

1.2: 1 h / Reflux

2.1: acetic acid; sulfuric acid / water / 1 h / Reflux

3.1: zinc(II) tetrahydroborate / tetrahydrofuran / Reflux

4.1: potassium carbonate; N,N'-dimethylbenzylamine / water / 1 h / 20 - 25 °C

4.2: 1 h / 20 - 25 °C / pH 10

4.3: 0.17 h

With N,N'-dimethylbenzylamine; zinc(II) tetrahydroborate; sulfuric acid; potassium carbonate; acetic acid; In tetrahydrofuran; ethanol; water;

DOI:10.1134/S1066362218010071

Reference yield:

2-phenyl[1-14C]acetic acid (51146-16-8) → Toluol-p-sulfonsaeure-2-phenyl-<1-14C>ethylester (41936-78-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: zinc(II) tetrahydroborate / tetrahydrofuran / Reflux

2.1: potassium carbonate; N,N'-dimethylbenzylamine / water / 1 h / 20 - 25 °C

2.2: 1 h / 20 - 25 °C / pH 10

2.3: 0.17 h

With N,N'-dimethylbenzylamine; zinc(II) tetrahydroborate; potassium carbonate; In tetrahydrofuran; water;

DOI:10.1134/S1066362218010071

upstream raw materials:

benzyl [cyano-¹⁴C] cyanide

2-phenyl[1-¹⁴C]ethanol

p-toluenesulfonyl chloride

benzyl chloride