51146-16-8

Upstream product

• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 4701-32-0 benzyl [cyano-¹⁴C] cyanide 

Downstream Products

• 53553-62-1 1,1,2-Triphenyl-aethanol-1-¹⁴C 
• 3979-14-4 tropic acid ethyl ester 
• 92875-79-1 3-hydroxy-2-phenyl-propionic acid-1-¹⁴C 
• 4995-78-2 2-phenyl[1-¹⁴C]ethanol 
• 41936-78-1 Toluol-p-sulfonsaeure-2-phenyl-<1-¹⁴C>ethylester 

Relevant academic research and scientific papers

Preparation of Fentanyl Labeled with Carbon-14

A convenient synthetic pathway for 14C labeling of fentanyl [N-(1-phenethyl-4-piperidinyl)- propionanilide], a widely used narcotic analgesic agent, with good radiochemical yield was developed.

Buscopan labeled with carbon-14 and deuterium

Hyosine butyl bromide, the active ingredient in Buscopan, is an anticholinergic and antimuscarinic drug used to treat pain and discomfort caused by abdominal cramps. A straightforward synthesis of carbon-14– and deuterium-labeled Buscopan was developed using scopolamine, n-butyl-1-14C bromide, and n-butyl-2H9 bromide, respectively. In a second carbon-14 synthesis, the radioactive carbon was incorporated in the tropic acid moiety to follow its metabolism. Herein, we describe the detailed preparations of carbon-14– and deuterium-labeled Buscopan.

Microwave-assisted synthesis of (RS) methyl-2-([2′- 14C]4,6-dimethoxypyrimidin-2′-yloxy)-2-phenyl [1- 14C]ethanoate

We report here a facile synthesis of (RS) methyl-2-([2′- 14C]4,6-dimethoxypyrimidin-2′-yloxy)-2-phenyl [1- 14C]ethanoate under microwave irradiation. Copyright