2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1,4-dimethoxy-5-nitrobenzene

Base Information

• Chemical Name: 2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1,4-dimethoxy-5-nitrobenzene
• CAS No.: 1004782-76-6
• Molecular Formula: C₂₂H₂₇NO₁₃
• Molecular Weight: 513.455
• Mol file: 1004782-76-6.mol

Synonyms:2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1,4-dimethoxy-5-nitrobenzene

Chemical Property of 2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1,4-dimethoxy-5-nitrobenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1,4-dimethoxy-5-nitrobenzene

There total 2 articles about 2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1,4-dimethoxy-5-nitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

1,4-dimethoxy-2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)benzene (210817-42-8) → 6-chloro-2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1,4-dimethoxybenzene (1004782-85-7) + 5-chloro-2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1,4-dimethoxybenzene (1004782-77-7) + 2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1,4-dimethoxy-5-nitrobenzene (1004782-76-6)

Guidance literature:

With ammonium nitrate; acetyl chloride; In acetonitrile; at 20 ℃; for 2h;

DOI:10.1055/S-2007-990856

Reference yield: 39.0%

1,4-dimethoxy-2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)benzene (210817-42-8) → 5-chloro-2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1,4-dimethoxybenzene (1004782-77-7) + 2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1,4-dimethoxy-5-nitrobenzene (1004782-76-6) + C22H26Cl2O11 (1004782-86-8)

Guidance literature:

With ammonium nitrate; phosphorus pentoxide; acetyl chloride; for 0.666667h;

DOI:10.1055/S-2007-990856

Reference yield: 82.0%

2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1,4-dimethoxy-5-nitrobenzene (1004782-76-6) → 4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-2,5-dimethoxyaniline (1004782-80-2)

Guidance literature:

With ammonium formate; palladium on activated charcoal; In methanol; at 20 ℃; for 1.25h;

DOI:10.1055/S-2007-990856

upstream raw materials:

1,4-dimethoxy-2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)benzene

Downstream raw materials:

4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-2,5-dimethoxyaniline