Technology Process of tert-Butyl-diphenyl-(4,4,7,7-tetramethyl-4,7-dihydro-oxepin-2-yloxy)-silane
There total 3 articles about tert-Butyl-diphenyl-(4,4,7,7-tetramethyl-4,7-dihydro-oxepin-2-yloxy)-silane which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) n-butyllithium, 2.) lithium bromide / 1.) THF, hexane, -41 deg C, 1 h, 2.) a) -41 deg C, 1 h, b) 25 deg C, 18 h
2: 90 percent / H2, quinoline / 5percent Pd/BaSO4 / methanol / 760 Torr
3: 1.) lithium diisopropylamide, 2.) HMPA / 1.) THF, -70 deg C, 20 min, 2.) from -70 deg C to RT, 2 h
With
quinoline; N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; hydrogen; lithium bromide; lithium diisopropyl amide;
Pd-BaSO4;
In
methanol;
DOI:10.1021/jo00205a035
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 90 percent / H2, quinoline / 5percent Pd/BaSO4 / methanol / 760 Torr
2: 1.) lithium diisopropylamide, 2.) HMPA / 1.) THF, -70 deg C, 20 min, 2.) from -70 deg C to RT, 2 h
With
quinoline; N,N,N,N,N,N-hexamethylphosphoric triamide; hydrogen; lithium diisopropyl amide;
Pd-BaSO4;
In
methanol;
DOI:10.1021/jo00205a035
- Guidance literature:
-
With
N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide;
Yield given. Multistep reaction;
1.) THF, -70 deg C, 20 min, 2.) from -70 deg C to RT, 2 h;
DOI:10.1021/jo00205a035