4-(4-Bromophenoxy)phenol

Base Information

• Chemical Name: 4-(4-Bromophenoxy)phenol
• CAS No.: 13320-48-4
• Molecular Formula: C12H9 Br O2
• Molecular Weight: 265.106
• Hs Code.: 2909500000
• European Community (EC) Number: 627-203-2
• DSSTox Substance ID: DTXSID60574237
• Nikkaji Number: J357.648E
• Wikidata: Q82463218
• Mol file: 13320-48-4.mol

Synonyms:4-(4-Bromophenoxy)phenol;13320-48-4;Phenol, 4-(4-bromophenoxy)-;4-(4-Bromo-phenoxy)-phenol;SCHEMBL7938161;DTXSID60574237;HMBBTPMHPQGJMR-UHFFFAOYSA-N;4-(4-Bromophenoxy)phenol, 97%;MFCD08446910;AKOS002679790;BS-53090;CS-0186868;D97307;J-006331

Chemical Property of 4-(4-Bromophenoxy)phenol

Chemical Property:

• Vapor Pressure: 1.15E-05mmHg at 25°C
• Melting Point: 73-78 °C
• Refractive Index: 1.631
• Boiling Point: 359.5°C at 760 mmHg
• PKA: 9.92±0.15(Predicted)
• Flash Point: 171.2°C
• PSA: 29.46000
• Density: 1.518g/cm³
• LogP: 3.94700
• Storage Temp.: 2-8°C
• XLogP3: 4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 263.97859
• Heavy Atom Count: 15
• Complexity: 182

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-(4-Bromophenoxy)phenol ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,N
• Statements: 36-43-51/53
• Safety Statements: 26-36/37-61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1O)OC2=CC=C(C=C2)Br

Technology Process of 4-(4-Bromophenoxy)phenol

There total 15 articles about 4-(4-Bromophenoxy)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

→ 4-hydroxy-4'-bromodiphenyl ether (13320-48-4)

Guidance literature:

With methanol; copper(II) ferrite; at 20 ℃; for 24h;

Reference yield: 80.0%

hydroquinone (123-31-9,8027-02-9) + 1-Bromo-4-fluorobenzene (460-00-4) → 1,4-Bis(p-bromophenoxy)benzene (41318-76-7) + 4-hydroxy-4'-bromodiphenyl ether (13320-48-4)

Guidance literature:

With potassium tert-butylate; In dimethyl sulfoxide; at 170 ℃; for 24h;

DOI:10.1016/j.tetlet.2005.09.025

Reference yield: 65.0%

hydroquinone (123-31-9,8027-02-9) + 1-Bromo-4-fluorobenzene (460-00-4) → 4-hydroxy-4'-bromodiphenyl ether (13320-48-4)

Guidance literature:

With 18-crown-6 ether; potassium tert-butylate; In dimethyl sulfoxide; at 100 ℃; for 24h;

DOI:10.1016/j.tetlet.2005.09.025

upstream raw materials:

4-(4-bromophenoxy)phenyl acetate

4-(4-Bromo-phenoxy)-2,4,6-tri-tert-butyl-cyclohexa-2,5-dienone

hydrogen bromide

hydroquinone

Downstream raw materials:

1-bromo-4-(4-methoxyphenoxy)benzene

1-(2-(4-(4-bromophenoxy)phenoxy)ethyl)pyrrolidine

D-2-[p-(p-bromophenoxy)phenoxy]-propionic acid

2-[4-(4-Bromo-phenoxy)-phenoxy]-propionic acid ethyl ester