4-AMINO-1,2,5-OXADIAZOLE-3-CARBOXAMIDE

Base Information

• Chemical Name: 4-AMINO-1,2,5-OXADIAZOLE-3-CARBOXAMIDE
• CAS No.: 13300-88-4
• Molecular Formula: C3H4N4O2
• Molecular Weight: 128.09
• Hs Code.: 2934999090
• Mol file: 13300-88-4.mol

Synonyms:3-Furazancarboxamide,4-amino- (8CI);Furazancarboxamide, 4-amino-;4-Amino-1,2,5-oxadiazole-3-carboxamide;

Chemical Property of 4-AMINO-1,2,5-OXADIAZOLE-3-CARBOXAMIDE

Chemical Property:

• Vapor Pressure: 6.13E-05mmHg at 25°C
• Refractive Index: 1.617
• Boiling Point: 345.5 °C at 760 mmHg
• Flash Point: 162.8 °C
• PSA: 108.03000
• Density: 1.608g/cm³
• LogP: 0.03220

Purity/Quality:

98%Min ^*data from raw suppliers

4-Amino-1,2,5-oxadiazole-3-carboxamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-AMINO-1,2,5-OXADIAZOLE-3-CARBOXAMIDE

There total 13 articles about 4-AMINO-1,2,5-OXADIAZOLE-3-CARBOXAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

n-propyl 4-amino[1,2,5]oxadiazole-3-carboxylate (1390648-48-2) → 4-amino-1,2,5-oxadiazole-3-carboxylic acid amide (13300-88-4)

Guidance literature:

With ammonium hydroxide; at 20 ℃; for 4.5h; Heating;

DOI:10.1002/jhet.1547

Reference yield: 90.0%

ethyl 4-amino-1,2,5-oxadiazole-3-carboxylate (17376-63-5) → 4-amino-1,2,5-oxadiazole-3-carboxylic acid amide (13300-88-4)

Guidance literature:

With ammonia; In ethanol; at 20 ℃;

DOI:10.1023/A:1012425408024

Reference yield: 62.0%

3,6-bis(4-amino-1,2,5-oxadiazol-3-yl)-1,4,2,5-dioxadiazine (147085-15-2) → 4-amino-1,2,5-oxadiazole-3-carboxylic acid amide (13300-88-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In N,N-dimethyl-formamide; at 30 ℃; for 6h; under 2280 Torr;

DOI:10.1007/BF00475263

upstream raw materials:

2-oxy-furazan-3,4-dicarboxylic acid diamide

(cyano-furazan-3-yl)-carbamic acid

formic acid

4-amino-N-hydroxy-furazan-3-carboxamidine

Downstream raw materials:

3-amino-1,2,5-oxadiazole-4-carbonitrile

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