tert-butyl (E)-2-(2-hydroxyphenylcarbonyl)-3-(naphthalen-2-yl)prop-2-enoate

Base Information

Chemical Name:tert-butyl (E)-2-(2-hydroxyphenylcarbonyl)-3-(naphthalen-2-yl)prop-2-enoate
CAS No.:936183-54-9
Molecular Formula:C₂₄H₂₂O₄
Molecular Weight:374.436
Hs Code.:

Synonyms:tert-butyl (E)-2-(2-hydroxyphenylcarbonyl)-3-(naphthalen-2-yl)prop-2-enoate

Suppliers and Price of tert-butyl (E)-2-(2-hydroxyphenylcarbonyl)-3-(naphthalen-2-yl)prop-2-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl (E)-2-(2-hydroxyphenylcarbonyl)-3-(naphthalen-2-yl)prop-2-enoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl (E)-2-(2-hydroxyphenylcarbonyl)-3-(naphthalen-2-yl)prop-2-enoate

There total 3 articles about tert-butyl (E)-2-(2-hydroxyphenylcarbonyl)-3-(naphthalen-2-yl)prop-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 936182-86-4
tert-butyl 3-(2-hydroxyphenyl)-3-oxopropanoate

: 66-99-9
β-naphthaldehyde

: 936183-54-9
tert-butyl (E)-2-(2-hydroxyphenylcarbonyl)-3-(naphthalen-2-yl)prop-2-enoate

Guidance literature:: With piperdinium acetate; sodium sulfate; In toluene; at 22 ℃; for 168h;
DOI:10.1021/ja070394v

Reference yield:

: 540-88-5
acetic acid tert-butyl ester

: 936183-54-9
tert-butyl (E)-2-(2-hydroxyphenylcarbonyl)-3-(naphthalen-2-yl)prop-2-enoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: (iPr)2NH; n-BuLi / tetrahydrofuran / 1.5 h / -78 °C

1.2: 75 percent / tetrahydrofuran / -78 - 20 °C

2.1: 58 percent / Na₂SO₄; piperidinium acetate / toluene / 168 h / 22 °C

With n-butyllithium; piperdinium acetate; sodium sulfate; diisopropylamine; In tetrahydrofuran; toluene; 2.1: Knoevenagel condensation;
DOI:10.1021/ja070394v

Reference yield:

: 118-61-6
2-hydroxy-benzoic acid ethyl ester

: 936183-54-9
tert-butyl (E)-2-(2-hydroxyphenylcarbonyl)-3-(naphthalen-2-yl)prop-2-enoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: (iPr)2NH; n-BuLi / tetrahydrofuran / 1.5 h / -78 °C

1.2: 75 percent / tetrahydrofuran / -78 - 20 °C

2.1: 58 percent / Na₂SO₄; piperidinium acetate / toluene / 168 h / 22 °C

With n-butyllithium; piperdinium acetate; sodium sulfate; diisopropylamine; In tetrahydrofuran; toluene; 2.1: Knoevenagel condensation;
DOI:10.1021/ja070394v