Technology Process of (3-bromo-4-methoxyphenyl)(2-ethylbenzofuran-3-yl)methanone
There total 4 articles about (3-bromo-4-methoxyphenyl)(2-ethylbenzofuran-3-yl)methanone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-ethylbenzofuran;
With
carbon disulfide;
for 0.5h;
Inert atmosphere;
Cooling with ice;
3-bromo-4-methoxy-benzoic acid chloride;
With
tin(IV) chloride;
at 20 ℃;
for 19h;
Cooling with ice;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: hydrazine / water; diethylene glycol / 120 - 190 °C
1.2: 6 h / 120 - 130 °C
2.1: carbon disulfide / 0.5 h / Inert atmosphere; Cooling with ice
2.2: 19 h / 20 °C / Cooling with ice
With
carbon disulfide; hydrazine;
In
water; diethylene glycol;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / acetone / 6 h / Reflux
2.1: hydrazine / water; diethylene glycol / 120 - 190 °C
2.2: 6 h / 120 - 130 °C
3.1: carbon disulfide / 0.5 h / Inert atmosphere; Cooling with ice
3.2: 19 h / 20 °C / Cooling with ice
With
carbon disulfide; potassium carbonate; hydrazine;
In
water; acetone; diethylene glycol;
