(R)-tert-butyl 4-[(S)-2-methoxycarbonyl-1-benzyloxyethyl]-2,2-dimethyloxazolidine-3-carboxylate

Base Information

Chemical Name:(R)-tert-butyl 4-[(S)-2-methoxycarbonyl-1-benzyloxyethyl]-2,2-dimethyloxazolidine-3-carboxylate
CAS No.:1181105-37-2
Molecular Formula:C₂₁H₃₁NO₆
Molecular Weight:393.48
Hs Code.:

Synonyms:(R)-tert-butyl 4-[(S)-2-methoxycarbonyl-1-benzyloxyethyl]-2,2-dimethyloxazolidine-3-carboxylate

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Chemical Property of (R)-tert-butyl 4-[(S)-2-methoxycarbonyl-1-benzyloxyethyl]-2,2-dimethyloxazolidine-3-carboxylate

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Technology Process of (R)-tert-butyl 4-[(S)-2-methoxycarbonyl-1-benzyloxyethyl]-2,2-dimethyloxazolidine-3-carboxylate

There total 1 articles about (R)-tert-butyl 4-[(S)-2-methoxycarbonyl-1-benzyloxyethyl]-2,2-dimethyloxazolidine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1181105-35-0
C₂₀H₂₉NO₆

: 74-88-4
methyl iodide

: 1181105-37-2
(R)-tert-butyl 4-[(S)-2-methoxycarbonyl-1-benzyloxyethyl]-2,2-dimethyloxazolidine-3-carboxylate

: 1181105-36-1
(R)-tert-butyl 4-[(R)-2-methoxycarbonyl-1-benzyloxyethyl]-2,2-dimethyloxazolidine-3-carboxylate

Guidance literature:: With potassium carbonate; In acetone; for 1h; optical yield given as %de; Reflux;
DOI:10.1016/j.tet.2009.05.054

Reference yield: 73.0%

: 1181105-37-2
(R)-tert-butyl 4-[(S)-2-methoxycarbonyl-1-benzyloxyethyl]-2,2-dimethyloxazolidine-3-carboxylate

: 142993-14-4
tert-butyl (3R,4S)-4-benzyloxytetrahydro-6-oxo-2H-pyran-3-ylcarbamate

: 1181105-39-4
C₁₈H₂₇NO₆

Guidance literature:: With acetic acid; In water; at 20 ℃; for 24h;
DOI:10.1016/j.tet.2009.05.054

Reference yield:

: 1181105-37-2
(R)-tert-butyl 4-[(S)-2-methoxycarbonyl-1-benzyloxyethyl]-2,2-dimethyloxazolidine-3-carboxylate

: 142993-12-2
C₁₇H₂₅NO₆

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / water / 24 h / 20 °C

2: sodium hydroxide / methanol; water / 3 h / 20 °C

With acetic acid; sodium hydroxide; In methanol; water;
DOI:10.1016/j.tet.2009.05.054