(S)-2-tert-butoxycarbonylamino-4-{6-methoxy-4-[4-(2-oxo-2-phenyl-ethyl)-phenoxy]-quinolin-7-yloxy}-butyric acid cyclopentyl ester

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Chemical Name:(S)-2-tert-butoxycarbonylamino-4-{6-methoxy-4-[4-(2-oxo-2-phenyl-ethyl)-phenoxy]-quinolin-7-yloxy}-butyric acid cyclopentyl ester
CAS No.:914490-67-8
Molecular Formula:C₃₈H₄₂N₂O₈
Molecular Weight:654.76
Hs Code.:

Synonyms:(S)-2-tert-butoxycarbonylamino-4-{6-methoxy-4-[4-(2-oxo-2-phenyl-ethyl)-phenoxy]-quinolin-7-yloxy}-butyric acid cyclopentyl ester

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Chemical Property of (S)-2-tert-butoxycarbonylamino-4-{6-methoxy-4-[4-(2-oxo-2-phenyl-ethyl)-phenoxy]-quinolin-7-yloxy}-butyric acid cyclopentyl ester

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Technology Process of (S)-2-tert-butoxycarbonylamino-4-{6-methoxy-4-[4-(2-oxo-2-phenyl-ethyl)-phenoxy]-quinolin-7-yloxy}-butyric acid cyclopentyl ester

There total 10 articles about (S)-2-tert-butoxycarbonylamino-4-{6-methoxy-4-[4-(2-oxo-2-phenyl-ethyl)-phenoxy]-quinolin-7-yloxy}-butyric acid cyclopentyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 914382-65-3
(S)-4-bromo-2-tert-butoxycarbonylamino-butyric acid cyclopentyl ester

: 914490-66-7
2-[4-(7-hydroxy-6-methoxy-quinolin-4-yloxy)-phenyl]-1-phenyl-ethanone

: 914490-67-8
(S)-2-tert-butoxycarbonylamino-4-{6-methoxy-4-[4-(2-oxo-2-phenyl-ethyl)-phenoxy]-quinolin-7-yloxy}-butyric acid cyclopentyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 35 ℃; for 20h;

Reference yield:

: 24845-40-7
2-(4-methoxyphenyl)acetophenone

: 914490-67-8
(S)-2-tert-butoxycarbonylamino-4-{6-methoxy-4-[4-(2-oxo-2-phenyl-ethyl)-phenoxy]-quinolin-7-yloxy}-butyric acid cyclopentyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogen bromide / 1 h / 120 °C

2: N,N-dimethyl-formamide / 5 h / 145 °C

3: ethanol; cyclohexene / palladium on activated charcoal / 2 h / Heating / reflux

4: potassium carbonate / N,N-dimethyl-formamide / 20 h / 35 °C

With ethanol; hydrogen bromide; potassium carbonate; cyclohexene; palladium on activated charcoal; In N,N-dimethyl-formamide;

Reference yield:

: 914490-65-6
2-[4-(7-benzyloxy-6-methoxy-quinolin-4-yloxy)-phenyl]-1-phenyl-ethanone

: 914490-67-8
(S)-2-tert-butoxycarbonylamino-4-{6-methoxy-4-[4-(2-oxo-2-phenyl-ethyl)-phenoxy]-quinolin-7-yloxy}-butyric acid cyclopentyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol; cyclohexene / palladium on activated charcoal / 2 h / Heating / reflux

2: potassium carbonate / N,N-dimethyl-formamide / 20 h / 35 °C

With ethanol; potassium carbonate; cyclohexene; palladium on activated charcoal; In N,N-dimethyl-formamide;