2-(3-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)propylthio)-5-phenyl-1,3,4-oxadiazole

Base Information

Chemical Name:2-(3-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)propylthio)-5-phenyl-1,3,4-oxadiazole
CAS No.:1333383-20-2
Molecular Formula:C₂₂H₂₃N₅OS₂
Molecular Weight:437.59
Hs Code.:

Synonyms:2-(3-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)propylthio)-5-phenyl-1,3,4-oxadiazole

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Chemical Property of 2-(3-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)propylthio)-5-phenyl-1,3,4-oxadiazole

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Technology Process of 2-(3-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)propylthio)-5-phenyl-1,3,4-oxadiazole

There total 5 articles about 2-(3-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)propylthio)-5-phenyl-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1333383-36-0
2-[(3-bromopropyl)thio]-5-phenyl-1,3,4-oxadiazole

: 87691-88-1,133070-64-1,144010-02-6
3-(1-piperazinyl)-1,2-benzisothiazole hydrochloride

: 1333383-20-2
2-(3-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)propylthio)-5-phenyl-1,3,4-oxadiazole

Guidance literature:: With potassium carbonate; potassium iodide; In acetonitrile; for 24h; Reflux;

Reference yield:

: 93-89-0,99341-95-4
benzoic acid ethyl ester

: 1333383-20-2
2-(3-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)propylthio)-5-phenyl-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 4 steps

1: hydrazine hydrate / ethanol / 8 h / Reflux

2: potassium hydroxide / ethanol / 6 h / Reflux

3: potassium hydroxide / acetonitrile / 1 h / Reflux

4: potassium carbonate; potassium iodide / acetonitrile / 24 h / Reflux

With potassium carbonate; hydrazine hydrate; potassium iodide; potassium hydroxide; In ethanol; acetonitrile;

Reference yield:

: 613-94-5
benzoic acid hydrazide

: 1333383-20-2
2-(3-(4-(1,2-benzisothiazole-3-yl)-1-piperazinyl)propylthio)-5-phenyl-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 3 steps

1: potassium hydroxide / ethanol / 6 h / Reflux

2: potassium hydroxide / acetonitrile / 1 h / Reflux

3: potassium carbonate; potassium iodide / acetonitrile / 24 h / Reflux

With potassium carbonate; potassium iodide; potassium hydroxide; In ethanol; acetonitrile;