(3'S)-3'-tert-butoxycarbonylamino-2',3'-dideoxy-2'-methylidene-5'-O-trityluridine

Base Information

Chemical Name:(3'S)-3'-tert-butoxycarbonylamino-2',3'-dideoxy-2'-methylidene-5'-O-trityluridine
CAS No.:142688-43-5
Molecular Formula:C₃₄H₃₅N₃O₆
Molecular Weight:581.668
Hs Code.:

Synonyms:(3'S)-3'-tert-butoxycarbonylamino-2',3'-dideoxy-2'-methylidene-5'-O-trityluridine

Suppliers and Price of (3'S)-3'-tert-butoxycarbonylamino-2',3'-dideoxy-2'-methylidene-5'-O-trityluridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3'S)-3'-tert-butoxycarbonylamino-2',3'-dideoxy-2'-methylidene-5'-O-trityluridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3'S)-3'-tert-butoxycarbonylamino-2',3'-dideoxy-2'-methylidene-5'-O-trityluridine

There total 8 articles about (3'S)-3'-tert-butoxycarbonylamino-2',3'-dideoxy-2'-methylidene-5'-O-trityluridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 4248-19-5
tert-butyl carbazate

: 142688-42-4
2',3'-didehydro-2',3'-dideoxy-2'-phenylselenomethyl-5'-O-trityluridine

: 142688-43-5
(3'S)-3'-tert-butoxycarbonylamino-2',3'-dideoxy-2'-methylidene-5'-O-trityluridine

Guidance literature:: With N-chloro-succinimide; triethylamine; In tetrahydrofuran; methanol; at -78 - -21 ℃; for 3h;
DOI:10.1016/S0040-4020(01)80786-9

Reference yield:

: 142688-37-7
Methanesulfonic acid (2R,3S,5R)-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-methylene-2-trityloxymethyl-tetrahydro-furan-3-yl ester

: 142688-43-5
(3'S)-3'-tert-butoxycarbonylamino-2',3'-dideoxy-2'-methylidene-5'-O-trityluridine

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / ethanol / 4 h / Ambient temperature

2: 73 percent / NCS, Et₃N / tetrahydrofuran; methanol / 3 h / -78 - -21 °C

With N-chloro-succinimide; triethylamine; In tetrahydrofuran; methanol; ethanol;
DOI:10.1016/S0040-4020(01)80786-9

Reference yield:

: 142688-36-6
2'-deoxy-2'-methylidene-5'-O-trityluridine

: 142688-43-5
(3'S)-3'-tert-butoxycarbonylamino-2',3'-dideoxy-2'-methylidene-5'-O-trityluridine

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / CH₂Cl₂ / 0.25 h / 0 °C

2: 96 percent / ethanol / 4 h / Ambient temperature

3: 73 percent / NCS, Et₃N / tetrahydrofuran; methanol / 3 h / -78 - -21 °C

With N-chloro-succinimide; triethylamine; In tetrahydrofuran; methanol; ethanol; dichloromethane;
DOI:10.1016/S0040-4020(01)80786-9