N-(3-benzoyl-4-aminophenyl)-3-[5-(4-carbamoylphenyl)-2-furyl]acrylic acid amide

Base Information

Chemical Name:N-(3-benzoyl-4-aminophenyl)-3-[5-(4-carbamoylphenyl)-2-furyl]acrylic acid amide
CAS No.:765938-41-8
Molecular Formula:C₂₇H₂₁N₃O₄
Molecular Weight:451.481
Hs Code.:

Synonyms:N-(3-benzoyl-4-aminophenyl)-3-[5-(4-carbamoylphenyl)-2-furyl]acrylic acid amide

Suppliers and Price of N-(3-benzoyl-4-aminophenyl)-3-[5-(4-carbamoylphenyl)-2-furyl]acrylic acid amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(3-benzoyl-4-aminophenyl)-3-[5-(4-carbamoylphenyl)-2-furyl]acrylic acid amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(3-benzoyl-4-aminophenyl)-3-[5-(4-carbamoylphenyl)-2-furyl]acrylic acid amide

There total 6 articles about N-(3-benzoyl-4-aminophenyl)-3-[5-(4-carbamoylphenyl)-2-furyl]acrylic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 765938-39-4
N-(3-benzoyl-4-trifluoroacetylaminophenyl)-3-[5-(4-cyanophenyl)-2-furyl]acrylic acid amide

: 765938-41-8
N-(3-benzoyl-4-aminophenyl)-3-[5-(4-carbamoylphenyl)-2-furyl]acrylic acid amide

Guidance literature:: With sodium hydroxide; dihydrogen peroxide; In 1,4-dioxane; ethanol; water; at 60 ℃; for 2h;
DOI:10.1016/j.bmc.2004.07.010

Reference yield:

: 1899-24-7
5-bromo-2-furancarboxaldehyde

: 765938-41-8
N-(3-benzoyl-4-aminophenyl)-3-[5-(4-carbamoylphenyl)-2-furyl]acrylic acid amide

Guidance literature:: Multi-step reaction with 5 steps

1: 46 percent / potassium carbonate / tetrakis(triphenylphosphine)palladium⁽⁰⁾; [1,1'-bis(diphenylphosphino)ferrocene]palladium(II) chloride / toluene; H₂O; ethanol / 5 h / Heating

2: 64 percent / pyridine; piperidine / 2 h / Heating

3: thionyl chloride / toluene / 2 h / Heating

4: 72 percent / toluene / 2 h / Heating

5: 79 percent / sodium hydroxide; H₂O₂ / ethanol; dioxane; H₂O / 2 h / 60 °C

With piperidine; pyridine; sodium hydroxide; thionyl chloride; dihydrogen peroxide; potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; ethanol; water; toluene; 1: Suzuki coupling / 2: Knoevenagel condensation;
DOI:10.1016/j.bmc.2004.07.010

Reference yield:

: 126747-14-6
4-cyanophenylboronic acid

: 765938-41-8
N-(3-benzoyl-4-aminophenyl)-3-[5-(4-carbamoylphenyl)-2-furyl]acrylic acid amide

Guidance literature:: Multi-step reaction with 5 steps

1: 46 percent / potassium carbonate / tetrakis(triphenylphosphine)palladium⁽⁰⁾; [1,1'-bis(diphenylphosphino)ferrocene]palladium(II) chloride / toluene; H₂O; ethanol / 5 h / Heating

2: 64 percent / pyridine; piperidine / 2 h / Heating

3: thionyl chloride / toluene / 2 h / Heating

4: 72 percent / toluene / 2 h / Heating

5: 79 percent / sodium hydroxide; H₂O₂ / ethanol; dioxane; H₂O / 2 h / 60 °C

With piperidine; pyridine; sodium hydroxide; thionyl chloride; dihydrogen peroxide; potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; ethanol; water; toluene; 1: Suzuki coupling / 2: Knoevenagel condensation;
DOI:10.1016/j.bmc.2004.07.010