(E)-4-methoxycinnamyl phenylpropiolate

Base Information

• Chemical Name: (E)-4-methoxycinnamyl phenylpropiolate
• CAS No.: 120981-39-7
• Molecular Formula: C₁₉H₁₆O₃
• Molecular Weight: 292.334
• Mol file: 120981-39-7.mol

Synonyms:(E)-4-methoxycinnamyl phenylpropiolate

Chemical Property of (E)-4-methoxycinnamyl phenylpropiolate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-4-methoxycinnamyl phenylpropiolate

There total 1 articles about (E)-4-methoxycinnamyl phenylpropiolate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

(E)-p-methoxy-cinnamyl alcohol (53484-50-7) + phenylpropyolic acid (637-44-5) → (E)-4-methoxycinnamyl phenylpropiolate (120981-39-7)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 1h; Ambient temperature;

DOI:10.1002/hlca.19880710716

Reference yield:

(E)-4-methoxycinnamyl phenylpropiolate (120981-39-7) → cis-transoid-3a,4,9,9a-tetrahydro-4-(4-methoxyphenyl)naphtho<2,3-c>furan-1(3H)-one

Guidance literature:

Multi-step reaction with 2 steps

1: 68 percent / H₂, quinoline / Lindlar catalyst / ethyl acetate / 760 Torr

2: 65 percent / dimethylformamide / 14 h / Heating

With quinoline; hydrogen; Lindlar's catalyst; In ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1002/hlca.19880710716

upstream raw materials:

(E)-p-methoxy-cinnamyl alcohol

phenylpropyolic acid