dithiophosphoric acid O-(4-acetylamino-phenyl) ester O'-(4-amino-phenyl) ester S-(2,4-dinitro-benzyl) ester

Base Information

• Chemical Name: dithiophosphoric acid O-(4-acetylamino-phenyl) ester O'-(4-amino-phenyl) ester S-(2,4-dinitro-benzyl) ester
• CAS No.: 251459-91-3
• Molecular Formula: C₂₁H₁₉N₄O₇PS₂
• Molecular Weight: 534.51
• Mol file: 251459-91-3.mol

Synonyms:dithiophosphoric acid O-(4-acetylamino-phenyl) ester O'-(4-amino-phenyl) ester S-(2,4-dinitro-benzyl) ester

Chemical Property of dithiophosphoric acid O-(4-acetylamino-phenyl) ester O'-(4-amino-phenyl) ester S-(2,4-dinitro-benzyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dithiophosphoric acid O-(4-acetylamino-phenyl) ester O'-(4-amino-phenyl) ester S-(2,4-dinitro-benzyl) ester

There total 5 articles about dithiophosphoric acid O-(4-acetylamino-phenyl) ester O'-(4-amino-phenyl) ester S-(2,4-dinitro-benzyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

{4-[(4-acetylamino-phenoxy)-(2,4-dinitro-benzylsulfanyl)-thiophosphoryloxy]-phenyl}-carbamic acid tert-butyl ester (251459-90-2) → dithiophosphoric acid O-(4-acetylamino-phenyl) ester O'-(4-amino-phenyl) ester S-(2,4-dinitro-benzyl) ester (251459-91-3)

Guidance literature:

With trifluoroacetic acid; In dichloromethane;

DOI:10.1016/S0040-4039(99)01501-4

Reference yield:

2,4-dinitrobenzyl chloride (610-57-1) → dithiophosphoric acid O-(4-acetylamino-phenyl) ester O'-(4-amino-phenyl) ester S-(2,4-dinitro-benzyl) ester (251459-91-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / lutidine

2: 99 percent / TFA / CH₂Cl₂

With lutidine; trifluoroacetic acid; In dichloromethane; 1: Substitution / 2: deprotection;

DOI:10.1016/S0040-4039(99)01501-4

Reference yield:

4-N-tert-butoxycarbonylaminophenol (54840-15-2) → dithiophosphoric acid O-(4-acetylamino-phenyl) ester O'-(4-amino-phenyl) ester S-(2,4-dinitro-benzyl) ester (251459-91-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 74 percent

2: 89 percent / lutidine

3: 99 percent / TFA / CH₂Cl₂

With lutidine; trifluoroacetic acid; In dichloromethane; 1: Substitution / 2: Substitution / 3: deprotection;

DOI:10.1016/S0040-4039(99)01501-4

upstream raw materials:

{4-[(4-acetylamino-phenoxy)-(2,4-dinitro-benzylsulfanyl)-thiophosphoryloxy]-phenyl}-carbamic acid tert-butyl ester

2,4-dinitrobenzyl chloride

4-N-tert-butoxycarbonylaminophenol

Downstream raw materials:

4-{4-[(4-acetylamino-phenoxy)-(2,4-dinitro-benzylsulfanyl)-thiophosphoryloxy]-phenylcarbamoyl}-butyric acid