tertbutyl N-(3-{[(3S,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyl-decahydronaphthalen-2-yl]amino}propyl)carbamate

Base Information

Chemical Name:tertbutyl N-(3-{[(3S,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyl-decahydronaphthalen-2-yl]amino}propyl)carbamate
CAS No.:1619984-05-2
Molecular Formula:C₃₁H₅₀N₂O₄
Molecular Weight:514.749
Hs Code.:

Synonyms:tertbutyl N-(3-{[(3S,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyl-decahydronaphthalen-2-yl]amino}propyl)carbamate

Suppliers and Price of tertbutyl N-(3-{[(3S,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyl-decahydronaphthalen-2-yl]amino}propyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tertbutyl N-(3-{[(3S,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyl-decahydronaphthalen-2-yl]amino}propyl)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tertbutyl N-(3-{[(3S,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyl-decahydronaphthalen-2-yl]amino}propyl)carbamate

There total 5 articles about tertbutyl N-(3-{[(3S,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyl-decahydronaphthalen-2-yl]amino}propyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 1619982-83-0
(3R,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-one

: 75178-96-0
N-Boc-1,3-diaminopropane

: 1619984-05-2
tertbutyl N-(3-{[(3S,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyl-decahydronaphthalen-2-yl]amino}propyl)carbamate

Guidance literature:: (3R,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-one; N-Boc-1,3-diaminopropane; With acetic acid; In tetrahydrofuran; at 20 ℃; for 0.666667h; Inert atmosphere;

With sodium tris(acetoxy)borohydride; In tetrahydrofuran; for 48h;

Reference yield:

: 1619982-82-9
(2R,3R,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyldecahydronaphthalen-2-ol

: 1619984-05-2
tertbutyl N-(3-{[(3S,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyl-decahydronaphthalen-2-yl]amino}propyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: pyridinium chlorochromate / dichloromethane / 2 h / Inert atmosphere

2.1: acetic acid / tetrahydrofuran / 0.67 h / 20 °C / Inert atmosphere

2.2: 48 h

With acetic acid; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane;

Reference yield:

: 1000009-66-4
(1S,2R,4aS,8aS)-1-[hydroxy(3-methoxy-5-methylphenyl)methyl]-2,5,5,8a-tetramethyldecahydronaphthalen-2-ol

: 1619984-05-2
tertbutyl N-(3-{[(3S,4S,4aS,8aS)-4-[(3-methoxy-5-methylphenyl)carbonyl]-3,4a,8,8-tetramethyl-decahydronaphthalen-2-yl]amino}propyl)carbamate

Guidance literature:: Multi-step reaction with 5 steps

1.1: pyridinium chlorochromate / dichloromethane / 1.5 h / 20 °C / Inert atmosphere

2.1: tin(IV) chloride / dichloromethane / 0.17 h / 0 °C / Inert atmosphere

3.1: borane-THF / tetrahydrofuran / 2 h / 0 - 20 °C / Inert atmosphere

3.2: 0.5 h / 0 - 20 °C

4.1: pyridinium chlorochromate / dichloromethane / 2 h / Inert atmosphere

5.1: acetic acid / tetrahydrofuran / 0.67 h / 20 °C / Inert atmosphere

5.2: 48 h

With borane-THF; tin(IV) chloride; acetic acid; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane;