N-(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-N'-piperidin-3-yl-guanidine

Base Information

Chemical Name:N-(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-N'-piperidin-3-yl-guanidine
CAS No.:1583272-58-5
Molecular Formula:C₁₁H₁₇ClN₈O
Molecular Weight:312.762
Hs Code.:

Synonyms:N-(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-N'-piperidin-3-yl-guanidine

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Chemical Property of N-(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-N'-piperidin-3-yl-guanidine

Chemical Property:

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Technology Process of N-(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-N'-piperidin-3-yl-guanidine

There total 1 articles about N-(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-N'-piperidin-3-yl-guanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 775530-61-5
3,5-diamino-6-chloro-N-[(methylsulfanyl)methanimidoyl]pyrazine-2-carboxamide

: 625471-18-3
tert-butyl (3S)-3-aminopiperidine-1-carboxylate

: 1583272-58-5
N-(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-N'-piperidin-3-yl-guanidine

Guidance literature:: 3,5-diamino-6-chloro-N-[(methylsulfanyl)methanimidoyl]pyrazine-2-carboxamide; tert-butyl (3S)-3-aminopiperidine-1-carboxylate; With triethylamine; In N,N-dimethyl-formamide; isopropyl alcohol; at 70 ℃;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

Reference yield:

: 1583272-58-5
N-(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-N'-piperidin-3-yl-guanidine

: 1129-28-8
3-methoxycarbonylbenzyl bromide

: 1610619-91-4
(S)-3-{3-[N'-(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-guanidino]-piperidin-1-ylmethyl}-benzoic acid methyl ester

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 6h;

Reference yield:

: 1583272-58-5
N-(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-N'-piperidin-3-yl-guanidine

: 1583272-44-9
(S)-3-[N'-(3,5-diamino-6-chloro-pyrazine-2-carbonyl)-guanidino]-1-(3-methoxycarbonyl-benzyl)-1-methyl-piperidinium chloride

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / N,N-dimethyl-formamide / 6 h / 20 °C

2: N,N-dimethyl-formamide; acetone / 20 °C

With triethylamine; In N,N-dimethyl-formamide; acetone;